2. Gene
  3. Cib1 - calcium and integrin binding 1 (calmyrin) Gene

Cib1 - calcium and integrin binding 1 (calmyrin) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Kip; Cibkip; Prkdcip

基因 ID: 23991 | 基因类型: protein coding

关于 Cib1

功能概要

Enables protein-membrane adaptor activity and transmembrane transporter binding activity. Involved in several processes, including negative regulation of megakaryocyte differentiation; regulation of intracellular signal transduction; and regulation of protein phosphorylation. Located in cytoplasm and sarcolemma. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human CIB1 (calcium and Integrin binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Cib1 基因产物(3)

mRNA Protein Name
NM_001291275.1 NP_001278204.1 calcium and integrin-binding protein 1 isoform 2
NM_001291276.1 NP_001278205.1 calcium and integrin-binding protein 1 isoform 3
NM_011870.5 NP_036000.1 calcium and integrin-binding protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20639889 MGI
enables protein-membrane adaptor activity IMP
IMP: 通过突变表型推断
20639889 MGI
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
20639889 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to growth factor stimulus IDA
IDA: 通过直接分析推断
17975111 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
16982698 MGI
involved in negative regulation of megakaryocyte differentiation IMP
IMP: 通过突变表型推断
22128142 MGI
involved in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
22128142 MGI
involved in negative regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
22128142 MGI
involved in platelet formation IMP
IMP: 通过突变表型推断
22128142 MGI
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
17975111 MGI
involved in positive regulation of calcineurin-NFAT signaling cascade IMP
IMP: 通过突变表型推断
20639889 MGI
involved in positive regulation of catalytic activity IMP
IMP: 通过突变表型推断
17975111 MGI
involved in positive regulation of cell growth IMP
IMP: 通过突变表型推断
16982698 MGI
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
22128142 MGI
involved in positive regulation of cell migration involved in sprouting angiogenesis IMP
IMP: 通过突变表型推断
17975111 MGI
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17975111 MGI
involved in positive regulation of cell-matrix adhesion IMP
IMP: 通过突变表型推断
22128142 MGI
involved in positive regulation of male germ cell proliferation IMP
IMP: 通过突变表型推断
16982698 MGI
involved in positive regulation of protein localization to plasma membrane IMP
IMP: 通过突变表型推断
20639889 MGI
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
17975111 MGI
involved in positive regulation of protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
17975111 MGI
involved in response to ischemia IDA
IDA: 通过直接分析推断
17975111 MGI
involved in spermatid development IMP
IMP: 通过突变表型推断
16982698 MGI
involved in thrombopoietin-mediated signaling pathway IMP
IMP: 通过突变表型推断
22128142 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
20639889 MGI
located in cytoplasm IMP
IMP: 通过突变表型推断
10366599 MGI
located in membrane IDA
IDA: 通过直接分析推断
10366599 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
20639889 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calcium and integrin-binding protein 1

CIB

DNA-PKcs-interacting protein

calcium and integrin binding, protein kinase interacting protein

calmyrin

kinase-interacting protein

protein kinase, DNA activated, catalytic polypeptide interacting protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-162558 NCGC00351170 Inhibitor 99.05% 否
HY-RS02706 CIB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19584 Cib1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26081 Cib1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cib1 NCBI NCBI:10519
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