2. Gene
  3. Adamts4 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 Gene

Adamts4 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ADMP-1; ADAM-TS4; ADAMTS-2

基因 ID: 240913 | 基因类型: protein coding

关于 Adamts4

功能概要

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active zinc-dependent aggrecanase enzyme that degrades cartilage. [provided by RefSeq, Jul 2016]

Adamts4 基因产物(1)

mRNA Protein Name
NM_172845.3 NP_766433.2 A disintegrin and metalloproteinase with thrombospondin motifs 4 preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables metalloendopeptidase activity IDA
IDA: 通过直接分析推断
23684986 MGI
enables metallopeptidase activity IDA
IDA: 通过直接分析推断
15192113 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23684986 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within defense response to bacterium IGI
IGI: 通过遗传相互作用推断
23684986 MGI
acts upstream of or within proteolysis IDA
IDA: 通过直接分析推断
15192113 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

A disintegrin and metalloproteinase with thrombospondin motifs 4

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4

aggrecanase-1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-137430 Aldumastat Inhibitor 99.36% Phase 2
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101448 TMI-1 99.57% 否
HY-114996 ADAMTS-5 Inhibitor Inhibitor 99.59% 否
HY-P10398 5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA 91.94% 否
HY-145061 ADAMTS-5-IN-3 Inhibitor 98.89% 否
HY-P5419A WAAG-3R TFA 99.75% 否
HY-P10468 5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 / 否
HY-RS00303 ADAMTS3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00304 ADAMTS4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-160822 AGG-523 Inhibitor / 否
HY-RS18103 Adamts4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24577 Adamts4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adamts4 NCBI NCBI:9507
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