1. Gene
  2. Adh1 - alcohol dehydrogenase 1C (class I), gamma polypeptide Gene

Adh1 - alcohol dehydrogenase 1C (class I), gamma polypeptide Gene

种属: Rattus norvegicus

同用名: Adh; Adh1a; Adh1c

基因 ID: 24172 | 基因类型: protein coding

关于 Adh1

功能概要

Enables NAD binding activity; ethanol binding activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in several processes, including acetaldehyde biosynthetic process; ethanol oxidation; and response to progesterone. Located in cytosol. Human ortholog(s) of this gene implicated in alcohol use disorder; late onset Parkinson's disease; and pancreatic Cancer. Orthologous to human ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide); ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide); and ADH1C (alcohol dehydrogenase 1C (class I), gamma polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Adh1 基因产物(1)

mRNA Protein Name
NM_019286.4 NP_062159.3 alcohol dehydrogenase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alcohol dehydrogenase (NAD+) activity IDA
IDA: 通过直接分析推断
1558299 RGD
enables all-trans-retinol dehydrogenase (NAD+) activity IDA
IDA: 通过直接分析推断
2940107 RGD
enables organic cyclic compound binding IPI
IPI: 通过物理相互作用推断
16385241 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
17126819 RGD
involved in lipid metabolic process IDA
IDA: 通过直接分析推断
10094961 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
23413777 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
18219182 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

alcohol dehydrogenase 1

alcohol dehydrogenase (class I), alpha polypeptide

alcohol dehydrogenase 1 (class I)

alcohol dehydrogenase 1, complex

alcohol dehydrogenase A subunit