1. Gene
  2. Cbs - cystathionine beta synthase Gene

Cbs - cystathionine beta synthase Gene

种属: Rattus norvegicus

基因 ID: 24250 | 基因类型: protein coding

关于 Cbs

功能概要

Enables cystathionine beta-synthase activity. Involved in several processes, including cellular response to hypoxia; hydrogen sulfide biosynthetic process; and transsulfuration. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Biomarker of hyperhomocysteinemia and vitamin B12 deficiency. Human ortholog(s) of this gene implicated in coronary artery disease; homocystinuria; hyperhomocysteinemia; malaria; and neural tube defect. Orthologous to human CBS (cystathionine beta-synthase). [provided by Alliance of Genome Resources, Apr 2022]

Cbs 基因产物(1)

mRNA Protein Name
NM_012522.2 NP_036654.2 cystathionine beta-synthase
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IDA
IDA: 通过直接分析推断
20149843 RGD
involved in hydrogen sulfide biosynthetic process IDA
IDA: 通过直接分析推断
20149843 RGD
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
20149843 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19352060 RGD
involved in transsulfuration IDA
IDA: 通过直接分析推断
16636197 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cystathionine beta-synthase

beta-thionase

hemoprotein H-450

serine sulfhydrase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cbs NCBI NCBI:875
Mus musculus Cbs NCBI NCBI:12411