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  2. Ets1 - ETS proto-oncogene 1, transcription factor Gene

Ets1 - ETS proto-oncogene 1, transcription factor Gene

种属: Rattus norvegicus

同用名: Tpl1; Ets-1; Etsoncb

基因 ID: 24356 | 基因类型: protein coding

关于 Ets1

功能概要

Enables Histone Acetyltransferase binding activity and sequence-specific DNA binding activity. Involved in several processes, including angiogenesis involved in wound healing; diencephalon development; and estrous cycle. Located in nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Ets1 基因产物(1)

mRNA Protein Name
NM_012555.2 NP_036687.1 protein C-ets-1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone acetyltransferase binding IPI
IPI: 通过物理相互作用推断
22357921 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12145332 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8635216 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis involved in wound healing IEP
IEP: 通过表达模式推断
9600079 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
16192649 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
18439600 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
18439600 RGD
involved in hypothalamus development IEP
IEP: 通过表达模式推断
8946059 RGD
involved in pituitary gland development IEP
IEP: 通过表达模式推断
8946059 RGD
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
12725417 RGD
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
19148472 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15806297 RGD
involved in regulation of extracellular matrix disassembly IMP
IMP: 通过突变表型推断
16738537 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
12725417 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
15579511 RGD
involved in response to interleukin-1 IEP
IEP: 通过表达模式推断
16046515 RGD
involved in response to laminar fluid shear stress IEP
IEP: 通过表达模式推断
18636553 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
18272346 RGD
involved in response to salt IEP
IEP: 通过表达模式推断
31932071 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein C-ets-1

Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1)

p54

v-ets avian erythroblastosis virus E26 oncogene homolog 1

v-ets erythroblastosis virus E26 oncogene homolog 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ets1 NCBI NCBI:2113