1. Gene
  2. Ano2 - anoctamin 2 Gene

Ano2 - anoctamin 2 Gene

种属: Mus musculus

同用名: Tmem16b

基因 ID: 243634 | 基因类型: protein coding

关于 Ano2

功能概要

Enables identical protein binding activity and intracellular calcium activated Chloride Channel activity. Acts upstream of or within chloride transport. Located in non-motile cilium and plasma membrane. Is expressed in dorsal root ganglion; epidermis; medulla oblongata basal plate mantle layer; olfactory epithelium; and spinal cord mantle layer. Orthologous to human ANO2 (anoctamin 2). [provided by Alliance of Genome Resources, Apr 2022]

Ano2 基因产物(3)

mRNA Protein Name
NM_001364562.1 NP_001351491.1 anoctamin-2 isoform 2
NM_001364563.1 NP_001351492.1 anoctamin-2 isoform 3
NM_153589.2 NP_705817.2 anoctamin-2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
23576756 MGI
enables intracellularly calcium-gated chloride channel activity IDA
IDA: 通过直接分析推断
19474308 MGI
enables intracellularly calcium-gated chloride channel activity IMP
IMP: 通过突变表型推断
21516098 MGI
NOT enables phospholipid scramblase activity IDA
IDA: 通过直接分析推断
23532839 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19474308 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chloride transport IDA
IDA: 通过直接分析推断
20056604 MGI
acts upstream of or within chloride transport IMP
IMP: 通过突变表型推断
21516098 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: 通过直接分析推断
23532839 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
21516098 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
19474308 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
21516098 MGI
located in non-motile cilium IDA
IDA: 通过直接分析推断
21516098 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
19474308 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
19474308 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

anoctamin-2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ano2 NCBI NCBI:57101