2. Gene
  3. Irf1 - interferon regulatory factor 1 Gene

Irf1 - interferon regulatory factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24508 | 基因类型: protein coding

关于 Irf1

功能概要

Enables sequence-specific DNA binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to exogenous dsRNA; and response to peptide hormone. Located in nucleus. Used to study endometrial adenocarcinoma. Biomarker of allergic conjunctivitis; lung disease; respiratory syncytial virus infectious disease; and ureteral obstruction. Human ortholog(s) of this gene implicated in asthma; gastric adenocarcinoma; lung non-small cell carcinoma; and smallpox. Orthologous to human IRF1 (interferon regulatory factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Irf1 基因产物(1)

mRNA Protein Name
NM_012591.2 NP_036723.2 interferon regulatory factor 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11880315 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
15141302 RGD
involved in cellular response to exogenous dsRNA IEP
IEP: 通过表达模式推断
11694343 RGD
involved in cellular response to interferon-beta IEP
IEP: 通过表达模式推断
21261980 RGD
involved in cellular response to peptide hormone stimulus IDA
IDA: 通过直接分析推断
11022129 RGD
involved in cellular response to retinoic acid IEP
IEP: 通过表达模式推断
15721283 RGD
involved in cellular response to tumor necrosis factor IDA
IDA: 通过直接分析推断
16978650 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
21261980 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
17651018 RGD
involved in negative regulation of protein modification process IMP
IMP: 通过突变表型推断
20980260 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
21261980 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11742807 RGD
involved in response to growth hormone IDA
IDA: 通过直接分析推断
9492014 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon regulatory factor 1

IRF-1

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-171006 IRF1-IN-1 Inhibitor 99.72% 否
HY-133897 (Rac)-Indoximod 99.18% 否
HY-108052 Delphinidin 3-glucoside chloride 99.89% 否
HY-Y0148 10-Hydroxydecanoic acid Inhibitor 98.77% 否
HY-171007 IRF1-IN-2 99.83% 否
HY-RS06902 IRF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-176222 IRF1 antagonist 1 Inhibitor / 否
HY-RS16716 Irf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23151 Irf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Irf1 NCBI NCBI:3659
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