1. Gene
  2. Oas2 - 2'-5' oligoadenylate synthetase 2 Gene

Oas2 - 2'-5' oligoadenylate synthetase 2 Gene

种属: Mus musculus

同用名: Oasl11

基因 ID: 246728 | 基因类型: protein coding

关于 Oas2

功能概要

Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in defense response to virus; regulation of lactation; and type I interferon signaling pathway. Acts upstream of or within RNA catabolic process; interleukin-27-mediated signaling pathway; and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol; membrane; and nucleoplasm. Is expressed in embryo. Orthologous to human OAS2 (2'-5'-oligoadenylate synthetase 2). [provided by Alliance of Genome Resources, Apr 2022]

Oas2 基因产物(2)

mRNA Protein Name
NM_001347448.1 NP_001334377.1 2'-5'-oligoadenylate synthase 2 isoform 1
NM_145227.3 NP_660262.2 2'-5'-oligoadenylate synthase 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 2'-5'-oligoadenylate synthetase activity IDA
IDA: 通过直接分析推断
12396720 MGI
enables double-stranded RNA binding IDA
IDA: 通过直接分析推断
12396720 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within RNA catabolic process IDA
IDA: 通过直接分析推断
15865429 MGI
involved in defense response to virus IDA
IDA: 通过直接分析推断
29117179 MGI
involved in interleukin-27-mediated signaling pathway IEP
IEP: 通过表达模式推断
32270034 MGI
involved in regulation of lactation IMP
IMP: 通过突变表型推断
29117179 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
involved in type I interferon-mediated signaling pathway IDA
IDA: 通过直接分析推断
29117179 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

2'-5'-oligoadenylate synthase 2

(2-5')oligo(A) synthase 2

2',5'-oligoadenylate synthetase-like 11

2,5-oligoadenylate synthetase-like 11

2-5A synthase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Oas2 NCBI NCBI:4939