2. Gene
  3. Gipr - gastric inhibitory polypeptide receptor Gene

Gipr - gastric inhibitory polypeptide receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gippr; RATGIPPR

基因 ID: 25024 | 基因类型: protein coding

关于 Gipr

功能概要

Enables gastric inhibitory peptide receptor activity and peptide hormone binding activity. Involved in several processes, including desensitization of G protein-coupled receptor signaling pathway; positive regulation of cell communication; and response to glucose. Located in plasma membrane. Used to study type 2 diabetes mellitus. Biomarker of hyperglycemia. Human ortholog(s) of this gene implicated in cardiovascular system disease; diabetes mellitus; and obesity. Orthologous to human GIPR (gastric inhibitory polypeptide receptor). [provided by Alliance of Genome Resources, Apr 2022]

Gipr 基因产物(2)

mRNA Protein Name
NM_012714.2 NP_036846.1 gastric inhibitory polypeptide receptor precursor
NM_012714.2 NP_036846.1 gastric inhibitory polypeptide receptor precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables gastric inhibitory peptide receptor activity IDA
IDA: 通过直接分析推断
8958204 RGD
enables peptide hormone binding IPI
IPI: 通过物理相互作用推断
8958204 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in desensitization of G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
8928774 RGD
involved in gastric inhibitory peptide signaling pathway IMP
IMP: 通过突变表型推断
11014226 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
8243312 RGD
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
11014226 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
19170165 RGD
involved in response to calcium ion IMP
IMP: 通过突变表型推断
9705086 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
12475913 RGD
involved in response to glucose IEP
IEP: 通过表达模式推断
12475913 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gastric inhibitory polypeptide receptor

GIP-R

gastric inhibitory peptide receptor

glucose-dependent insulinotropic polypeptide receptor

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P3506B Retatrutide acetate Agonist / Phase 3
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990047 Maridebart Inhibitor 98.23% Phase 3
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P3506 Retatrutide Agonist 99.96% 否
HY-P3506A Retatrutide TFA Agonist 99.10% 否
HY-P3584A (Pro3) GIP, human TFA 99.89% 否
HY-P10302A GLP-1R/GIPR agonist-1 (soduim) Agonist 98.24% 否
HY-P10271 RG7697 Agonist 99.90% 否
HY-P10302 GLP-1R/GIPR agonist-1 Agonist / 否
HY-P3584 (Pro3) GIP, human Agonist 99.79% 否
HY-173479 GLP-1R agonist 30 Agonist / 否
HY-P11321 IUB0271 / 否
HY-RS05437 GIPR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17884 Gipr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24353 Gipr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gipr NCBI NCBI:2696
Macaca fascicularis Gipr NCBI NCBI:102123760
Mus musculus Gipr NCBI NCBI:381853
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