2. Gene
  3. GATA1 - Gata1 GATA binding protein 1 Gene

GATA1 - Gata1 GATA binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Eryf1

基因 ID: 25172 | 基因类型: protein coding

关于 GATA1

功能概要

Enables chromatin binding activity and sequence-specific DNA binding activity. Involved in several processes, including Sertoli cell development; cellular response to cAMP; and cellular response to follicle-stimulating hormone stimulus. Located in nucleus. Biomarker of mental depression and polycythemia. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; X-linked recessive disease (multiple); bone marrow Cancer (multiple); colon adenocarcinoma; and myeloid leukemia associated with Down Syndrome. Orthologous to human GATA1 (GATA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

GATA1 基因产物(1)

mRNA Protein Name
NM_012764.2 NP_036896.1 erythroid transcription factor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
7957872 RGD
enables chromatin binding IDA
IDA: 通过直接分析推断
22885997 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
7957872 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Sertoli cell development IEP
IEP: 通过表达模式推断
9089398 RGD
involved in animal organ regeneration IDA
IDA: 通过直接分析推断
18990226 RGD
involved in cellular response to cAMP IEP
IEP: 通过表达模式推断
11861504 RGD
involved in cellular response to follicle-stimulating hormone stimulus IEP
IEP: 通过表达模式推断
11861504 RGD
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
17687519 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
22390417 RGD
involved in positive regulation of mast cell degranulation IMP
IMP: 通过突变表型推断
22390417 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

erythroid transcription factor

GATA-1

GATA-binding factor 1

GATA-binding protein 1 (globin transcription factor 1)

GF-1

NF-E1 DNA-binding protein

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P3761 Ac-Tyr-Val-Lys-Asp-aldehyde Inhibitor 99.89% 否
HY-RS05289 GATA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174677 Human GATA1 mRNA / 否
HY-RS20026 Gata1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26529 Gata1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens GATA1 NCBI NCBI:2623
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z