1. Gene
  2. Sdc2 - syndecan 2 Gene

Sdc2 - syndecan 2 Gene

种属: Rattus norvegicus

同用名: HSPG

基因 ID: 25615 | 基因类型: protein coding

关于 Sdc2

功能概要

Enables PDZ domain binding activity and identical protein binding activity. Involved in several processes, including dendrite morphogenesis; response to caffeine; and response to hypoxia. Located in neuronal cell body. Colocalizes with synapse. Human ortholog(s) of this gene implicated in cleft lip and cleft palate. Orthologous to human SDC2 (syndecan 2). [provided by Alliance of Genome Resources, Apr 2022]

Sdc2 基因产物(1)

mRNA Protein Name
NM_013082.4 NP_037214.1 syndecan-2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
9660869 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
26601939 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11356864 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendrite morphogenesis IEP
IEP: 通过表达模式推断
11580899 RGD
involved in regulation of synapse assembly IDA
IDA: 通过直接分析推断
17548511 RGD
involved in regulation of synapse assembly IMP
IMP: 通过突变表型推断
17548511 RGD
involved in regulation of synapse maturation IDA
IDA: 通过直接分析推断
9971750 RGD
involved in regulation of synapse maturation IMP
IMP: 通过突变表型推断
9971750 RGD
involved in response to caffeine IEP
IEP: 通过表达模式推断
16458123 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
18803305 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
9660869 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
9971750 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
10460248 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
9660869 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
9660869 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

syndecan-2

Ryudocan/syndecan 2

SYND2

fibroglycan

heparan sulfate proteoglycan core protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sdc2 NCBI NCBI:6383
Mus musculus Sdc2 NCBI NCBI:15529