2. Gene
  3. Cpe - carboxypeptidase E Gene

Cpe - carboxypeptidase E Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cph; CARBE

基因 ID: 25669 | 基因类型: protein coding

关于 Cpe

功能概要

Enables Carboxypeptidase activity; cobalt ion binding activity; and protein domain specific binding activity. Involved in negative regulation of branching morphogenesis of a nerve and peptide metabolic process. Located in several cellular components, including membrane raft; perikaryon; and secretory granule. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CPE (Carboxypeptidase E). [provided by Alliance of Genome Resources, Apr 2022]

Cpe 基因产物(1)

mRNA Protein Name
NM_013128.2 NP_037260.2 carboxypeptidase E precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carboxypeptidase activity IDA
IDA: 通过直接分析推断
2822027 RGD
enables cobalt ion binding IMP
IMP: 通过突变表型推断
2822027 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
2822027 RGD
enables protein domain specific binding IDA
IDA: 通过直接分析推断
19553464 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to dexamethasone stimulus IMP
IMP: 通过突变表型推断
25426952 RGD
involved in cellular response to hydrogen peroxide IMP
IMP: 通过突变表型推断
25426952 RGD
involved in cellular response to staurosporine IMP
IMP: 通过突变表型推断
25426952 RGD
involved in enkephalin processing IDA
IDA: 通过直接分析推断
6326144 RGD
involved in insulin processing IDA
IDA: 通过直接分析推断
2822027 RGD
involved in insulin processing IMP
IMP: 通过突变表型推断
12829804 RGD
involved in insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
12829804 RGD
involved in negative regulation of branching morphogenesis of a nerve IMP
IMP: 通过突变表型推断
19553464 RGD
involved in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
25426952 RGD
involved in neuron migration IMP
IMP: 通过突变表型推断
29982499 RGD
involved in neuron projection arborization IMP
IMP: 通过突变表型推断
29982499 RGD
involved in peptide catabolic process IDA
IDA: 通过直接分析推断
2822027 RGD
involved in peptide metabolic process IDA
IDA: 通过直接分析推断
16219686 RGD
involved in protein processing IDA
IDA: 通过直接分析推断
2822027 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
19166515 RGD
located in dendrite IDA
IDA: 通过直接分析推断
17543468 RGD
located in dense core granule IDA
IDA: 通过直接分析推断
19553464 RGD
located in extracellular region IDA
IDA: 通过直接分析推断
10386951 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
10206965 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
17543468 RGD
located in nucleus IDA
IDA: 通过直接分析推断
25426952 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
17543468 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
2822027 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
19553464 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

carboxypeptidase E

carboxypeptidase H

enkephalin convertase

prohormone-processing carboxypeptidase

相关产品

Pre-clinical Phase
生物活性分子 (14)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12928 ML336 Inhibitor 99.65% 否
HY-121528 Nilestriol 98.93% 否
HY-132169 HCoV-229E-IN-1 Inhibitor 99.16% 否
HY-12349 H1PVAT Inhibitor 96.40% 否
HY-175469 VNT-101 Inhibitor 99.51% 否
HY-106508 Fendosal Inhibitor / 否
HY-124938 ABC-1 / 否
HY-N15765 24:1 CPE (d18/24:1) / 否
HY-N15767 24:0 CPE (d18:1/24:0) / 否
HY-P11455 Lipopeptide CPE4 / 否
HY-RS03090 CPE Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174385 SARS-CoV-2-IN-114 Inhibitor / 否
HY-RS17120 Cpe Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23565 Cpe Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cpe NCBI NCBI:1363
Mus musculus Cpe NCBI NCBI:12876
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