MYH9 - Myh9 myosin, heavy chain 9 Gene

种属: Rattus norvegicus

同用名: NMIIA; Myh9l1

关于 MYH9

功能概要

Enables several functions, including G-protein alpha-subunit binding activity; follicle-stimulating hormone receptor binding activity; and scaffold protein binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; actin Cytoskeleton organization; and positive regulation of cell communication. Located in several cellular components, including actin filament; brush border; and lateral plasma membrane. Part of protein-containing complex. Colocalizes with endosome and phagocytic vesicle. Biomarker of metabolic acidosis. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autosomal dominant Alport syndrome; blood platelet disease (multiple); end stage renal disease; and orofacial cleft. Orthologous to human MYH9 (Myosin heavy chain 9). [provided by Alliance of Genome Resources, Apr 2022]