2. Gene
  3. Cpt1a - carnitine palmitoyltransferase 1A Gene

Cpt1a - carnitine palmitoyltransferase 1A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CPT-Ia

基因 ID: 25757 | 基因类型: protein coding

关于 Cpt1a

功能概要

Enables carnitine O-palmitoyltransferase activity and identical protein binding activity. Involved in several processes, including fatty acid metabolic process; liver regeneration; and response to tetrachloromethane. Located in mitochondrial outer membrane. Is integral component of mitochondrial outer membrane. Biomarker of alcoholic hepatitis; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency and lipid metabolism disorder. Orthologous to human CPT1A (carnitine palmitoyltransferase 1A). [provided by Alliance of Genome Resources, Apr 2022]

Cpt1a 基因产物(1)

mRNA Protein Name
NM_031559.2 NP_113747.2 carnitine O-palmitoyltransferase 1, liver isoform
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carnitine O-palmitoyltransferase activity IDA
IDA: 通过直接分析推断
11790778 RGD
enables carnitine O-palmitoyltransferase activity IMP
IMP: 通过突变表型推断
9169604 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
19136561 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19429947 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aflatoxin metabolic process IEP
IEP: 通过表达模式推断
28959666 RGD
involved in carnitine metabolic process IDA
IDA: 通过直接分析推断
21990363 RGD
involved in cellular response to fatty acid IEP
IEP: 通过表达模式推断
19332540 RGD
involved in eating behavior IMP
IMP: 通过突变表型推断
12754501 RGD
involved in fatty acid beta-oxidation IEP
IEP: 通过表达模式推断
31901136 RGD
involved in fatty acid metabolic process IDA
IDA: 通过直接分析推断
24222496 RGD
involved in fatty acid metabolic process IEP
IEP: 通过表达模式推断
30851372 RGD
involved in glucose metabolic process IMP
IMP: 通过突变表型推断
12754501 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
31953200 RGD
involved in long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
21990363 RGD
involved in long-chain fatty acid metabolic process IMP
IMP: 通过突变表型推断
19302064 RGD
involved in positive regulation of fatty acid beta-oxidation IMP
IMP: 通过突变表型推断
19302064 RGD
involved in regulation of fatty acid oxidation IMP
IMP: 通过突变表型推断
11988095 RGD
involved in regulation of insulin secretion IMP
IMP: 通过突变表型推断
11988095 RGD
involved in regulation of lipid storage IEP
IEP: 通过表达模式推断
27939985 RGD
involved in response to alkaloid IEP
IEP: 通过表达模式推断
30868489 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
27939985 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
33310031 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
33310031 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
30851372 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
16751799 RGD
involved in response to tetrachloromethane IEP
IEP: 通过表达模式推断
31918260 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19553925 RGD
involved in triglyceride metabolic process IMP
IMP: 通过突变表型推断
18349115 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
NOT located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
12401113 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
9169604 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

carnitine O-palmitoyltransferase 1, liver isoform

CPT I

CPT1-L

CPTI-L

carnitine palmitoyltransferase 1, liver

carnitine palmitoyltransferase 1a, liver

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-115938 BEC2 Inhibitor 98.0% Phase 3
Pre-clinical Phase
生物活性分子 (14)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-50202 Etomoxir Inducer 99.92% 是
HY-12364 C75 Inhibitor 99.91% 否
HY-50202A Etomoxir sodium salt Inducer 99.62% 是
HY-50670 DGAT-1 inhibitor 2 95.70% 否
HY-RS03122 CPT1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W588256 12-Tridecenoic acid Activator 95.0% 否
HY-W420033 (S)-(+)-Etomoxir Control 98.65% 否
HY-N8144 Niga-ichigoside F1 99.0% 否
HY-RS16248 Cpt1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-116257 GSK-7227 Agonist / 否
HY-12364B (−)-C75 Inhibitor / 否
HY-161027 DHP-B Inducer / 否
HY-N9333 Wistin Agonist / 否
HY-RS23138 Cpt1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cpt1a NCBI NCBI:1374
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