2. Gene
  3. INTS7 - integrator complex subunit 7 Gene

INTS7 - integrator complex subunit 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：整合复合物亚基 7

种属: Homo sapiens

同用名: INT7; C1orf73

基因 ID: 25896 | 基因类型: protein coding

关于 INTS7

Cytogenetic location: 1q32.3 Genomic coordinates (GRCh38): 1:211,940,403-212,035,557 (from NCBI)

This gene has 11 transcripts (splice variants) and 204 orthologues. Broad expression in testis (RPKM 9.9), lymph node (RPKM 3.5) and 24 other tissues.

功能概要

该基因编码整合复合体的一个亚基。整合复合物与 RNA 聚合酶 II 的 C 末端结构域相关联，并介导小核 RNA U1 和 U2 的 3' 末端加工。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2010 年 12 月]

This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

INTS7 基因产物(4)

mRNA Protein Name
NM_001199809.2 NP_001186738.1 integrator complex subunit 7 isoform 4
NM_001199811.2 NP_001186740.1 integrator complex subunit 7 isoform 2
NM_001199812.2 NP_001186741.1 integrator complex subunit 7 isoform 3
NM_015434.4 NP_056249.1 integrator complex subunit 7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16239144 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage checkpoint signaling IMP
IMP: 通过突变表型推断
21659603 GOA
involved in cellular response to ionizing radiation IDA
IDA: 通过直接分析推断
21659603 GOA
involved in snRNA processing IDA
IDA: 通过直接分析推断
16239144 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome IDA
IDA: 通过直接分析推断
21659603 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
23904267 GOA
part of integrator complex IDA
IDA: 通过直接分析推断
16239144 GOA
located in nucleus IDA
IDA: 通过直接分析推断
23904267 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integrator complex subunit 7

关联疾病

疾病名称 别名
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06857 INTS7 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus INTS7 RGD RGD:1308014
Felis catus INTS7 VGNC VGNC:62947
Macaca mulatta INTS7 VGNC VGNC:73644
Bos taurus INTS7 VGNC VGNC:30233
Canis familiaris INTS7 VGNC VGNC:42056
Mus musculus INTS7 MGD MGI:1924315
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