2. Gene
  3. ZNF521 - zinc finger protein 521 Gene

ZNF521 - zinc finger protein 521 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 521

种属: Homo sapiens

同用名: EHZF; Evi3

基因 ID: 25925 | 基因类型: protein coding

关于 ZNF521

Cytogenetic location: 18q11.2 Genomic coordinates (GRCh38): 18:25,061,924-25,352,166 (from NCBI)

This gene has 14 transcripts (splice variants), 210 orthologues, 7 paralogues and is associated with 92 phenotypes. Ubiquitous expression in ovary (RPKM 5.8), spleen (RPKM 5.0) and 22 other tissues.

功能概要

启用蛋白质域特异性结合活性。预计参与 RNA 聚合酶 II 的转录调控。预计在神经元命运承诺的上游或内部行动。位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein domain specific binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuron fate commitment. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF521 基因产物(2)

mRNA Protein Name
NM_001308225.2 NP_001295154.1 zinc finger protein 521 isoform 2
NM_015461.3 NP_056276.1 zinc finger protein 521 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
11984006 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12393497 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZNF521 蛋白结构

zf-C2H2_6

zf-C2H2_6: C2H2-type zinc finger (46 - 72)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (118 - 140)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (162 - 184)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (188 - 212)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (247 - 269)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (282 - 304)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (312 - 332)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (437 - 460)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (514 - 536)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (634 - 656)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (665 - 686)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (694 - 717)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (722 - 745)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (752 - 772)

zf-C2H2_6

zf-C2H2_6: C2H2-type zinc finger (809 - 832)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (888 - 909)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (944 - 968)

zf-C2H2_6

zf-C2H2_6: C2H2-type zinc finger (1064 - 1080)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1139 - 1161)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1195 - 1217)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1225 - 1247)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1256 - 1279)

  • 0
  • 300
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  • 1200
  • 1311 a.a.
蛋白主名 其他名称

zinc finger protein 521

LYST-interacting protein 3

关联疾病

疾病名称 别名
Invasive Bladder Transitional Cell Carcinoma

Invasive Bladder Urothelial Carcinoma

Infiltrating Bladder Urothelial Carcinoma
Gastrointestinal Neuroendocrine Benign Tumor
Gastric Neuroendocrine Neoplasm

Gastric Neuroendocrine Tumor

Neuroendocrine Tumor Of The Stomach

Neuroendocrine Tumor Of Stomach

Gnet

Gastric Net

Net Of Stomach
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16151 ZNF521 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ZNF521 VGNC VGNC:79444
Bos taurus ZNF521 VGNC VGNC:37296
Mus musculus ZNF521 MGD MGI:95459
Felis catus ZNF521 VGNC VGNC:67321
Canis familiaris ZNF521 VGNC VGNC:48750
Rattus norvegicus ZNF521 RGD RGD:1307345
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