1. Gene
  2. RGS22 - regulator of G protein signaling 22 Gene

RGS22 - regulator of G protein signaling 22 Gene

中文名称:G 蛋白信号调节因子 22

种属: Homo sapiens

同用名: CT145; PRTD-NY2

基因 ID: 26166 | 基因类型: protein coding

关于 RGS22

Cytogenetic location: 8q22.2 Genomic coordinates (GRCh38): 8:99,960,936-100,106,049 (from NCBI)

This gene has 17 transcripts (splice variants), 189 orthologues and 23 paralogues. Biased expression in testis (RPKM 35.2), ovary (RPKM 3.9) and 1 other tissue.

功能概要

启用 G 蛋白 α 亚基结合活性。预计参与信号转导的负调控。位于肌动蛋白细胞骨架;胞质溶胶;和纤维中心。 [由基因组资源联盟提供,2022 年 4 月]

Enables G-protein alpha-subunit binding activity. Predicted to be involved in negative regulation of signal transduction. Located in actin cytoskeleton; cytosol; and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

RGS22 基因产物(3)

mRNA Protein Name
NM_001286692.2 NP_001273621.1 regulator of G-protein signaling 22 isoform 2
NM_001286693.2 NP_001273622.1 regulator of G-protein signaling 22 isoform 3
NM_015668.5 NP_056483.3 regulator of G-protein signaling 22 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G-protein alpha-subunit binding IPI
IPI: 通过物理相互作用推断
18703424 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
18703424 GOA
located in nucleus IDA
IDA: 通过直接分析推断
18703424 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RGS22 蛋白结构

RGS

RGS: Regulator of G protein signaling domain (676 - 771)

RGS

RGS: Regulator of G protein signaling domain (853 - 977)

RGS

RGS: Regulator of G protein signaling domain (1022 - 1134)

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  • 1264 a.a.
蛋白主名 其他名称

regulator of G-protein signaling 22

直系同源

种属 基因名 来源 基因 ID
Canis familiaris RGS22 VGNC VGNC:45532
Rattus norvegicus RGS22 RGD RGD:1565493
Macaca mulatta RGS22 VGNC VGNC:82221
Mus musculus RGS22 MGD MGI:3613651
Felis catus RGS22 VGNC VGNC:81693
Bos taurus RGS22 VGNC VGNC:33921