2. Gene
  3. SIGLEC7 - sialic acid binding Ig like lectin 7 Gene

SIGLEC7 - sialic acid binding Ig like lectin 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：唾液酸结合 Ig 样凝集素 7

种属: Homo sapiens

同用名: p75; QA79; AIRM1; CD328; AIRM-1; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1

基因 ID: 27036 | 基因类型: protein coding

关于 SIGLEC7

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,142,301-51,153,526 (from NCBI)

This gene has 6 transcripts (splice variants), 79 orthologues and 16 paralogues. Broad expression in spleen (RPKM 7.6), appendix (RPKM 5.3) and 14 other tissues.

功能概要

预测启用唾液酸结合活性。预计参与细胞粘附。预计是质膜的组成部分。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SIGLEC7 基因产物(3)

mRNA Protein Name
NM_001277201.2 NP_001264130.1 sialic acid-binding Ig-like lectin 7 isoform 3 precursor
NM_014385.4 NP_055200.1 sialic acid-binding Ig-like lectin 7 isoform 1 precursor
NM_016543.4 NP_057627.2 sialic acid-binding Ig-like lectin 7 isoform 2 precursor

SIGLEC7 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (31 - 143)

Ig_3

Ig_3: Immunoglobulin domain (155 - 220)

Ig_2

Ig_2: Immunoglobulin domain (265 - 333)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 467 a.a.
蛋白主名 其他名称

sialic acid-binding Ig-like lectin 7

QA79 membrane protein

重组 SIGLEC7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71311 Siglec-7 Protein, Human (HEK293, His) Q9Y286 (Q19-L353) ≥95%

关联疾病

疾病名称 别名
Congenital Disorder Of Glycosylation, Type Iic

CDG2C

Congenital Disorder Of Glycosylation Type Iic

Leukocyte Adhesion Deficiency Type Ii

Cdg Iic

Cdgiic

Rambam-Hasharon Syndrome

Leukocyte Adhesion Deficiency, Type Ii

Lad2

Leukocyte Adhesion Deficiency 2

Cdg-Iic

Congenital Disorder Of Glycosylation, Type 2c

Rhs

Cdg Syndrome Type Iic

Lad-Ii

Rambam Hasharon Syndrome

Congenital Disorder Of Glycosylation 2c

Glycosylation, Congenital Disorder Of, Type Iic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70302 ST8 alpha-2,8-Sialyltransferase 6 / 否
HY-RS12905 SIGLEC7 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SIGLEC7 MGD MGI:1932475
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