2. Gene
  3. Wrn - WRN RecQ like helicase Gene

Wrn - WRN RecQ like helicase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RGD1564788

基因 ID: 290805 | 基因类型: protein coding

关于 Wrn

功能概要

Enables chromatin binding activity. Involved in brain development. Located in neuron projection. Human ortholog(s) of this gene implicated in Werner syndrome; breast cancer; coronary artery disease (multiple); diffuse scleroderma; and senile cataract. Orthologous to human WRN (WRN RecQ like helicase). [provided by Alliance of Genome Resources, Apr 2022]

Wrn 基因产物(2)

mRNA Protein Name
XM_006253256.4 XP_006253318.1 Werner syndrome ATP-dependent helicase isoform X1
XM_039095090.1 XP_038951018.1 Werner syndrome ATP-dependent helicase isoform X2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
19737542 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Werner syndrome ATP-dependent helicase

similar to Werner syndrome helicase homolog

Werner syndrome RecQ like helicase

Werner syndrome, RecQ helicase-like

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-148699 HRO761 Inhibitor 99.58% Phase 1
HY-158116 VVD-214 Inhibitor 99.76% Phase 1
Pre-clinical Phase
生物活性分子 (36)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12342 ML216 Inhibitor 99.89% 否
HY-110185 NSC 617145 Inhibitor 99.18% 否
HY-148740 Werner syndrome RecQ helicase-IN-3 Inhibitor 99.94% 否
HY-149887 H3B-968 98.22% 否
HY-128712 NCGC00029283 Inhibitor 98.88% 否
HY-162471 GSK_WRN3 Inhibitor 98.54% 否
HY-156579 WRN inhibitor 3 Inhibitor 99.54% 否
HY-156580 WRN inhibitor 4 Inhibitor 99.40% 否
HY-156581 WRN inhibitor 5 Inhibitor 98.12% 否
HY-163942 GSK_WRN4 Inhibitor 98.85% 否
HY-160859 WRN inhibitor 8 Inhibitor 98.07% 否
HY-169422 GSK4418959 Inhibitor / 否
HY-148741 Werner syndrome RecQ helicase-IN-4 Inhibitor 98.13% 否
HY-153692 WRN inhibitor 1 Inhibitor 98.05% 否
HY-163941 GSK_WRN2 95.95% 否
HY-148700 Werner syndrome RecQ helicase-IN-2 Inhibitor 99.32% 否
HY-153973 WRN inhibitor 2 / 否
HY-158025 Anticancer agent 198 Inhibitor / 否
HY-153692A (R)-WRN inhibitor 1 / 否
HY-157954 WRN inhibitor 6 / 否
HY-161386 WRN inhibitor 7 / 否
HY-163797 WRN inhibitor 10 Inhibitor / 否
HY-164852 WRN inhibitor 13 / 否
HY-168583 WRN inhibitor 11 Inhibitor / 否
HY-168592 WRN inhibitor 12 Inhibitor / 否
HY-168933 KWR095 Inhibitor / 否
HY-168934 KWR137 Inhibitor / 否
HY-169414 WRN inhibitor 15 / 否
HY-169423 WRN inhibitor 17 Inhibitor / 否
HY-169424 WRN inhibitor 18 Inhibitor / 否
HY-169928 WRN inhibitor 14 Inhibitor / 否
HY-174217 WRN-IN-19 Inhibitor / 否
HY-176727 WRN inhibitor 19 Inhibitor / 否
HY-RS15847 WRN Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS16538 Wrn Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS22970 Wrn Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wrn NCBI NCBI:7486
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