1. Gene
  2. Col4a1 - collagen type IV alpha 1 chain Gene

Col4a1 - collagen type IV alpha 1 chain Gene

种属: Rattus norvegicus

基因 ID: 290905 | 基因类型: protein coding

关于 Col4a1

功能概要

Predicted to enable platelet-derived growth factor binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in epithelial cell differentiation. Predicted to be located in extracellular region. Predicted to be part of Collagen type IV trimer. Predicted to be active in basement membrane and extracellular space. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in brain small vessel disease 1; myocardial infarction; and retinal arterial tortuosity. Orthologous to human COL4A1 (Collagen type IV alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col4a1 基因产物(1)

mRNA Protein Name
NM_001135009.1 NP_001128481.1 collagen alpha-1(IV) chain precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epithelial cell differentiation IEP
IEP: 通过表达模式推断
8635488 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

collagen alpha-1(IV) chain

alpha 1 type IV collagen

collagen, type IV, alpha 1

procollagen, type IV, alpha 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Col4a1 NCBI NCBI:1282