2. Gene
  3. Nqo2 - N-ribosyldihydronicotinamide:quinone reductase 2 Gene

Nqo2 - N-ribosyldihydronicotinamide:quinone reductase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 291084 | 基因类型: protein coding

关于 Nqo2

功能概要

Predicted to enable several functions, including anion binding activity; dihydronicotinamide riboside Quinone Reductase activity; and melatonin binding activity. Involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of neuron apoptotic process; and positive regulation of vascular associated smooth muscle cell proliferation. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Parkinson's disease; agranulocytosis; breast cancer; and breast carcinoma. Orthologous to human NQO2 (N-ribosyldihydronicotinamide:quinone reductase 2). [provided by Alliance of Genome Resources, Apr 2022]

Nqo2 基因产物(1)

mRNA Protein Name
NM_001004214.1 NP_001004214.1 ribosyldihydronicotinamide dehydrogenase [quinone]
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in memory IEP
IEP: 通过表达模式推断
17512093 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
23554738 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
20861374 RGD
involved in positive regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
23554738 RGD
involved in positive regulation of vascular associated smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
22508052 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ribosyldihydronicotinamide dehydrogenase [quinone]

NAD(P)H dehydrogenase, quinone 2

NAD(P)H quinone dehydrogenase 2

NRH dehydrogenase [quinone] 2

NRH:quinone oxidoreductase 2

QR2

quinone reductase 2

ribosyldihydronicotinamide dehydrogenase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-14895 Fabomotizole 99.96% 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-145820 Tubulin inhibitor 14 / Phase 3
HY-12346 FH1 Inhibitor 99.17% Phase 1
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-77521 Dabigatran ethyl ester hydrochloride Inhibitor / 否
HY-168926 NQO2-IN-1 Inducer 98.02% 否
HY-RS09524 NQO2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20312 Nqo2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26820 Nqo2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nqo2 NCBI NCBI:4835
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