2. Gene
  3. Arg2 - arginase 2 Gene

Arg2 - arginase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29215 | 基因类型: protein coding

关于 Arg2

功能概要

Enables Arginase activity and nitric-oxide synthase binding activity. Involved in several processes, including arginine catabolic process to ornithine; cellular response to cytokine stimulus; and cellular response to lipid. Located in mitochondrion. Used to study hypertension. Biomarker of acute kidney failure; end stage renal disease; hypertension; and ureteral obstruction. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (Arginase 2). [provided by Alliance of Genome Resources, Apr 2022]

Arg2 基因产物(1)

mRNA Protein Name
NM_019168.2 NP_062041.2 arginase-2, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables arginase activity IDA
IDA: 通过直接分析推断
11829529 RGD
enables nitric-oxide synthase binding IPI
IPI: 通过物理相互作用推断
16537391 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16537391 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in arginine catabolic process to ornithine IDA
IDA: 通过直接分析推断
15753084 RGD
involved in arginine metabolic process IMP
IMP: 通过突变表型推断
16537391 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
11250887 RGD
involved in cellular response to interleukin-4 IEP
IEP: 通过表达模式推断
14618299 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
11250887 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
11250887 RGD
involved in lung development IEP
IEP: 通过表达模式推断
18192591 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
16735458 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
10050048 RGD
involved in negative regulation of nitric-oxide synthase activity IMP
IMP: 通过突变表型推断
16537391 RGD
involved in negative regulation of striated muscle contraction IMP
IMP: 通过突变表型推断
16537391 RGD
involved in regulation of L-arginine import across plasma membrane IDA
IDA: 通过直接分析推断
11120661 RGD
involved in regulation of nitric oxide biosynthetic process IEP
IEP: 通过表达模式推断
11829529 RGD
involved in response to amine IEP
IEP: 通过表达模式推断
16168957 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
15458774 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
15735325 RGD
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
16570515 RGD
involved in response to glucose IEP
IEP: 通过表达模式推断
15254879 RGD
involved in response to herbicide IEP
IEP: 通过表达模式推断
20388547 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
14532164 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
20039818 RGD
involved in response to mercury ion IEP
IEP: 通过表达模式推断
17874066 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
18348861 RGD
involved in response to selenium ion IEP
IEP: 通过表达模式推断
14624471 RGD
involved in response to vitamin E IEP
IEP: 通过表达模式推断
14624471 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
15888029 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
16537391 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

arginase-2, mitochondrial

AII type II arginase

arginase II

arginase type II

kidney-type arginase

non-hepatic arginase

type II arginase

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-112885B nor-NOHA monoacetate Inhibitor 99.96% Phase 1
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112885C nor-NOHA dihydrochloride 98.85% 否
HY-112885A nor-NOHA acetate ≥99.0% 否
HY-RS00908 ARG2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P4750 Acetyl-(D-Arg2)-GRF (1-29) amide (human) Antagonist 99.67% 否
HY-112885 nor-NOHA / 否
HY-P10555 (D-Arg2, Sar 4)-Dermorphin (1-4) Agonist / 否
HY-RS17404 Arg2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23859 Arg2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arg2 NCBI NCBI:384
Mus musculus Arg2 NCBI NCBI:11847
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