1. Gene
  2. Fgf8 - fibroblast growth factor 8 Gene

Fgf8 - fibroblast growth factor 8 Gene

种属: Rattus norvegicus

同用名: Fgf6c

基因 ID: 29349 | 基因类型: protein coding

关于 Fgf8

功能概要

Enables chemoattractant activity. Involved in several processes, including neuron development; odontogenesis; and response to oxidative stress. Located in external side of plasma membrane. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 6 with or without anosmia and prostate carcinoma in situ. Orthologous to human FGF8 (Fibroblast Growth Factor 8). [provided by Alliance of Genome Resources, Apr 2022]

Fgf8 基因产物(2)

mRNA Protein Name
NM_001414191.1 NP_001401120.1 fibroblast growth factor 8 isoform 1 precursor
NM_133286.2 NP_579820.1 fibroblast growth factor 8 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemoattractant activity IMP
IMP: 通过突变表型推断
12403710 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in central nervous system neuron development IMP
IMP: 通过突变表型推断
9630220 RGD
involved in dorsal/ventral axon guidance IMP
IMP: 通过突变表型推断
12403710 RGD
involved in forebrain neuron development IMP
IMP: 通过突变表型推断
9630220 RGD
involved in motor neuron axon guidance IMP
IMP: 通过突变表型推断
12403710 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
19464577 RGD
involved in response to oxidative stress IDA
IDA: 通过直接分析推断
10350562 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
15786497 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
9531542 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

fibroblast growth factor 8

fibroblast growth factor 6c

fibroblast growth factor 8 (androgen-induced)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fgf8 NCBI NCBI:2253