Acvr1b - activin A receptor type 1B Gene

中文名称：激活素 A 受体 1B 型

种属: Rattus norvegicus

同用名: Skr2

关于 Acvr1b

功能概要

预计该基因编码的蛋白可启动多种功能，包括 ATP 绑定活动；激活素结合活性；和激活素受体活性，I 型。预计有助于激活素激活受体活性和生长因子结合活性。参与中枢神经系统发育；主要女性性特征的发展；氮化合物代谢过程的正向调控。预测位于细胞表面和胞质溶胶中。预计是质膜的组成部分。预计是激活素受体复合物的一部分。预计在质膜上有活性。该基因的人类直系同源物与胰腺癌有关。与人类 ACVR1B（1B 型激活素 A 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including ATP binding activity; activin binding activity; and activin receptor activity, type I. Predicted to contribute to activin-activated receptor activity and growth factor binding activity. Involved in central nervous system development; development of primary female sexual characteristics; and positive regulation of nitrogen compound metabolic process. Predicted to be located in cell surface and cytosol. Predicted to be integral component of plasma membrane. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human ACVR1B (Activin A receptor type 1B). [provided by Alliance of Genome Resources, Apr 2022]