2. Gene
  3. Ptbp1 - polypyrimidine tract binding protein 1 Gene

Ptbp1 - polypyrimidine tract binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ptb; PTB1; Pybp; Pybp1; Pybp2

基因 ID: 29497 | 基因类型: protein coding

关于 Ptbp1

功能概要

Enables nucleic acid binding activity and single-stranded DNA endodeoxyribonuclease activity. Involved in several processes, including mRNA metabolic process; positive regulation of cellular component organization; and positive regulation of gene expression. Located in cytoplasm; neuron projection terminus; and nucleus. Orthologous to human PTBP1 (polypyrimidine tract binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ptbp1 基因产物(2)

mRNA Protein Name
NM_001271057.1 NP_001257986.1 polypyrimidine tract-binding protein 1 isoform a
NM_022516.5 NP_071961.2 polypyrimidine tract-binding protein 1 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA binding IDA
IDA: 通过直接分析推断
19273590 RGD
enables regulatory region RNA binding IDA
IDA: 通过直接分析推断
23511971 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
1561080 RGD
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
1561080 RGD
enables single-stranded DNA endodeoxyribonuclease activity IDA
IDA: 通过直接分析推断
12269805 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 3'-UTR-mediated mRNA stabilization IDA
IDA: 通过直接分析推断
11696543 RGD
involved in cardiac ventricle development IEP
IEP: 通过表达模式推断
19590510 RGD
involved in mRNA processing IMP
IMP: 通过突变表型推断
16177139 RGD
involved in nuclear-transcribed mRNA catabolic process IMP
IMP: 通过突变表型推断
15039777 RGD
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
15039777 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
17400307 RGD
involved in positive regulation of secretory granule organization IMP
IMP: 通过突变表型推断
15039777 RGD
involved in positive regulation of translation IMP
IMP: 通过突变表型推断
19273590 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuron projection terminus IDA
IDA: 通过直接分析推断
17400307 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

polypyrimidine tract-binding protein 1

heterogeneous nuclear ribonucleoprotein I

hnRNP I

pyrimidine binding protein 1

pyrimidine binding protein 2

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P5960 PTBP1-RNA-binding inhibitor P6 TFA 99.49% 否
HY-167832 PT109 Inhibitor 99.20% 否
HY-P5959 PTBP1 α3-helix derived peptide P1 TFA Inhibitor 98.88% 否
HY-RS11351 PTBP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17773 Ptbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24240 Ptbp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptbp1 NCBI NCBI:5725
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