1. Gene
  2. Hnrnpa1 - heterogeneous nuclear ribonucleoprotein A1 Gene

Hnrnpa1 - heterogeneous nuclear ribonucleoprotein A1 Gene

种属: Rattus norvegicus

同用名: Hnrpa1; hnRNP A1

基因 ID: 29578 | 基因类型: protein coding

关于 Hnrnpa1

功能概要

Enables nucleic acid binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; cellular response to thapsigargin; and cellular response to tunicamycin. Located in cytosol and nucleoplasmic periphery of the nuclear pore complex. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 20; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3; and tropical spastic paraparesis. Orthologous to several human genes including HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpa1 基因产物(2)

mRNA Protein Name
NM_001399274.1 NP_001386203.1 heterogeneous nuclear ribonucleoprotein A1 isoform 1
NM_017248.3 NP_058944.2 heterogeneous nuclear ribonucleoprotein A1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA/DNA annealing activity IDA
IDA: 通过直接分析推断
1703006 RGD
enables RNA binding IDA
IDA: 通过直接分析推断
23159318 RGD
enables RNA strand annealing activity IDA
IDA: 通过直接分析推断
1703006 RGD
enables mRNA 3'-UTR binding IDA
IDA: 通过直接分析推断
11723238 RGD
enables mRNA binding IDA
IDA: 通过直接分析推断
23106379 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16518874 RGD
enables sequence-specific mRNA binding IDA
IDA: 通过直接分析推断
11886857 RGD
enables single-stranded RNA binding IDA
IDA: 通过直接分析推断
7727389 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
3062579 RGD
involved in cellular response to potassium ion IDA
IDA: 通过直接分析推断
17298175 RGD
involved in lung development IEP
IEP: 通过表达模式推断
9457472 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
10978504 RGD
involved in positive regulation of action potential IMP
IMP: 通过突变表型推断
15197740 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
23106379 RGD
involved in response to endoplasmic reticulum stress IEP
IEP: 通过表达模式推断
23106379 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleoplasmic periphery of the nuclear pore complex IDA
IDA: 通过直接分析推断
10633080 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

heterogeneous nuclear ribonucleoprotein A1

HDP

helix-destabilizing protein

hnRNP core protein A1

single-strand RNA-binding protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hnrnpa1 NCBI NCBI:3178