GTF2B - general transcription factor IIB Gene

中文名称：一般转录因子 IIB

种属: Homo sapiens

同用名: TF2B; TFIIB

关于 GTF2B

功能概要

该基因编码一般转录因子 IIB，这是 RNA 聚合酶 II 转录起始所需的普遍存在的因子之一。该蛋白质定位于细胞核，在那里它与转录因子 IID 和 IIA 形成复合物 (DAB 复合物) 。转录因子 IIB 充当 IID (最初识别启动子序列的因子) 和 RNA 聚合酶 II 之间的桥梁。[RefSeq 提供，2008 年 7 月]

This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008]