1. Gene
  2. Efemp1 - EGF containing fibulin extracellular matrix protein 1 Gene

Efemp1 - EGF containing fibulin extracellular matrix protein 1 Gene

种属: Rattus norvegicus

同用名: T16

基因 ID: 305604 | 基因类型: protein coding

关于 Efemp1

功能概要

Predicted to enable epidermal growth factor receptor binding activity and epidermal growth factor-activated receptor activity. Involved in positive regulation of cell population proliferation; regulation of cell projection organization; and regulation of glial cell migration. Located in basement membrane and cytoplasm. Human ortholog(s) of this gene implicated in Doyne honeycomb retinal dystrophy. Orthologous to human EFEMP1 (EGF containing fibulin extracellular Matrix Protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Efemp1 基因产物(1)

mRNA Protein Name
NM_001012039.1 NP_001012039.1 EGF-containing fibulin-like extracellular matrix protein 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9268694 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of neuron projection development IDA
IDA: 通过直接分析推断
18803302 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
18803302 RGD
involved in positive regulation of cell projection organization IDA
IDA: 通过直接分析推断
18803302 RGD
involved in positive regulation of cell projection organization IMP
IMP: 通过突变表型推断
18803302 RGD
involved in regulation of glial cell migration IDA
IDA: 通过直接分析推断
18803302 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
18803302 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

EGF-containing fibulin-like extracellular matrix protein 1

FIBL-3

epidermal growth factor-containing fibulin-like extracellular matrix protein 1

fibulin-3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Efemp1 NCBI NCBI:2202
Mus musculus Efemp1 NCBI NCBI:216616