1. Gene
  2. Sfrp2 - secreted frizzled-related protein 2 Gene

Sfrp2 - secreted frizzled-related protein 2 Gene

种属: Rattus norvegicus

基因 ID: 310552 | 基因类型: protein coding

关于 Sfrp2

功能概要

Predicted to enable several functions, including Wnt-protein binding activity; fibronectin binding activity; and signaling receptor binding activity. Involved in negative regulation of canonical Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; and response to nutrient. Predicted to be located in collagen-containing extracellular matrix. Predicted to be active in extracellular space. Biomarker of myocardial infarction. Orthologous to human SFRP2 (secreted Frizzled related protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Sfrp2 基因产物(1)

mRNA Protein Name
NM_001100700.1 NP_001094170.1 secreted frizzled-related protein 2 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
24080158 RGD
involved in positive regulation of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
24080158 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
17341692 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

secreted frizzled-related protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sfrp2 NCBI NCBI:6423
Macaca fascicularis Sfrp2 NCBI NCBI:102147309
Mus musculus Sfrp2 NCBI NCBI:20319