2. Gene
  3. Trpa1 - transient receptor potential cation channel, subfamily A, member 1 Gene

Trpa1 - transient receptor potential cation channel, subfamily A, member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Anktm1

基因 ID: 312896 | 基因类型: protein coding

关于 Trpa1

功能概要

Enables osmolarity-sensing cation channel activity and voltage-gated Calcium Channel activity. Involved in several processes, including cellular response to caffeine; positive regulation of transport; and regulation of nervous system process. Located in apical plasma membrane and axon. Used to study asthma and diabetic neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Orthologous to human TRPA1 (transient receptor potential cation channel subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Trpa1 基因产物(1)

mRNA Protein Name
NM_207608.2 NP_997491.2 transient receptor potential cation channel subfamily A member 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables osmolarity-sensing monoatomic cation channel activity IDA
IDA: 通过直接分析推断
18279313 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
20231274 RGD
enables voltage-gated calcium channel activity IDA
IDA: 通过直接分析推断
14712238 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium ion transmembrane import into cytosol IDA
IDA: 通过直接分析推断
14712238 RGD
involved in calcium ion transmembrane import into cytosol IMP
IMP: 通过突变表型推断
31969645 RGD
involved in cellular response to caffeine IEP
IEP: 通过表达模式推断
22319196 RGD
involved in cellular response to carbon dioxide IDA
IDA: 通过直接分析推断
20881114 RGD
involved in cellular response to cold IMP
IMP: 通过突变表型推断
21068322 RGD
involved in cellular response to heat IMP
IMP: 通过突变表型推断
22458587 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
22701540 RGD
involved in positive regulation of monoatomic anion transport IMP
IMP: 通过突变表型推断
22207576 RGD
involved in regulation of blood circulation IMP
IMP: 通过突变表型推断
22133672 RGD
involved in regulation of neuronal action potential IMP
IMP: 通过突变表型推断
20205719 RGD
involved in urinary bladder smooth muscle contraction IMP
IMP: 通过突变表型推断
21367919 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
22207576 RGD
located in axon IDA
IDA: 通过直接分析推断
18514429 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transient receptor potential cation channel subfamily A member 1

ankyrin-like with transmembrane domains protein 1

wasabi receptor

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-N6810 Thymol 99.97% 是
HY-B1173 (+)-Camphor Inhibitor 98.0% 否
HY-N6810R Thymol (Standard) 99.92% 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-108463 A-967079 Antagonist 99.30% Phase 1
HY-115877 GDC-0334 Antagonist / Phase 1
Pre-clinical Phase
生物活性分子 (58)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100965 Diphenyleneiodonium chloride 99.91% 否
HY-15064 HC-030031 Inhibitor 99.49% 否
HY-153169 6PPD-Q Inhibitor 99.30% 否
HY-N6825 Hydroxy-α-sanshool Agonist 99.57% 否
HY-101507 Zerencotrep Inhibitor 99.47% 否
HY-107436 LE135 99.0% 否
HY-135013 Umbellulone Activator 99.60% 否
HY-18662 RQ-00203078 Antagonist 99.84% 否
HY-111132 JT010 Agonist 99.48% 否
HY-101907 ASP7663 Agonist 99.16% 否
HY-N8264 Moringin Agonist 99.95% 否
HY-W014421 AP-18 Inhibitor 99.61% 否
HY-18779 PF-4840154 Agonist 98.15% 否
HY-121636 Resolvin D2 Inhibitor 99.90% 否
HY-108329 AM-0902 Antagonist 99.73% 否
HY-120689 PF-04745637 Antagonist 99.97% 否
HY-148236 BAY-390 Inhibitor 99.74% 否
HY-156684 Nedizantrep Inhibitor 99.77% 否
HY-121539 Supercinnamaldehyde Activator ≥99.0% 否
HY-N2318 Podocarpic acid Agonist 99.78% 否
HY-12809 Optovin Activator 99.81% 否
HY-W002116 Methyl syringate 99.96% 否
HY-107535 AS1269574 99.84% 否
HY-134098 Diisopropyl adipate Activator 99.90% 否
HY-15065 Chembridge-5861528 Antagonist 99.12% 否
HY-N10319 Artepillin C 98.28% 否
HY-114524 (E)-4-Oxo-2-nonenal Agonist 95.0% 否
HY-153711 TRPA1-IN-2 Inhibitor 99.82% 否
HY-N7117 1,4-Cineole Activator 95.0% 否
HY-P5914A Wasabi Receptor Toxin TFA Activator 99.49% 否
HY-171846 LY3526318 Inhibitor / 否
HY-121636S Resolvin D2-d5 Inhibitor 99.0% 否
HY-165559 Trpvicin Inhibitor 99.4% 否
HY-N7536 Voacangine 98.78% 否
HY-P5914 Wasabi Receptor Toxin Activator / 否
HY-W008356 2-Fluoro-4-iodobenzonitrile / 否
HY-W106234 4-(Phenyldiazenyl)benzoic acid Agonist 98.81% 否
HY-142214 TRPA1-IN-1 Antagonist / 否
HY-104061 AMG8788 Antagonist / 否
HY-104062 AMG9678 Antagonist / 否
HY-139904 TRPA1 Antagonist 3 Agonist / 否
HY-15056 AMG 9090 Agonist / 否
HY-170652 ZQMT-10 Inhibitor / 否
HY-172898 TRPA1-IN-4 Inhibitor / 否
HY-173471 TRPA1 agonist-1 Agonist / 否
HY-N12605 hTRPA1-IN-1 Inhibitor / 否
HY-N7965 Methyl kakuol Agonist / 否
HY-P10356 T100-Mut Inhibitor / 否
HY-RS15103 TRPA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W002116S Methyl syringate-d6 / 否
HY-W010270A Aurothiomalate disodium / 否
HY-159134 TRPA1-IN-3 Inhibitor 99.66% 否
HY-N10612 Petasin / 否
HY-RS16515 Trpa1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22946 Trpa1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W708469 Resolvin D2 methyl ester Inhibitor / 否
HY-111494 TRPA1 Antagonist 1 Inhibitor / 否
HY-113018 Ibuprofen acyl-β-D-glucuronide Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trpa1 NCBI NCBI:8989
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