1. Gene
  2. Vwc2 - von Willebrand factor C domain containing 2 Gene

Vwc2 - von Willebrand factor C domain containing 2 Gene

种属: Mus musculus

同用名: G11; UNQ739; cradin; PSST739; A930041G11Rik

基因 ID: 319922 | 基因类型: protein coding

关于 Vwc2

功能概要

Involved in negative regulation of BMP signaling pathway and positive regulation of neuron differentiation. Acts upstream of or within positive regulation of cell-substrate adhesion. Located in basement membrane; extracellular space; and interstitial matrix. Part of AMPA glutamate receptor complex. Is expressed in alimentary system; blood vessel; and nervous system. Orthologous to human VWC2 (von Willebrand factor C domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Vwc2 基因产物(1)

mRNA Protein Name
NM_177033.3 NP_796007.1 brorin precursor
基因本体论
  • 生物过程
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AMPA glutamate receptor complex IDA
IDA: 通过直接分析推断
22632720 MGI
located in basement membrane IDA
IDA: 通过直接分析推断
18757743 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
18757743 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
17400546 MGI
is active in extrinsic component of postsynaptic membrane IDA
IDA: 通过直接分析推断
37591201 MGI
is active in extrinsic component of postsynaptic membrane IMP
IMP: 通过突变表型推断
37591201 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
37591201 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
37591201 MGI
located in interstitial matrix IDA
IDA: 通过直接分析推断
18757743 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

brorin

CR (chordin-like cysteine-rich) domain-containing adhesive protein

brain-specific chordin-like protein

von Willebrand factor C domain-containing protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vwc2 NCBI NCBI:375567