1. Gene
  2. Itgb8 - integrin beta 8 Gene

Itgb8 - integrin beta 8 Gene

种属: Mus musculus

同用名: 4832412O06Rik

基因 ID: 320910 | 基因类型: protein coding

关于 Itgb8

功能概要

Predicted to enable extracellular matrix protein binding activity and Integrin binding activity. Involved in regulation of transforming growth factor beta activation. Acts upstream of or within several processes, including Langerhans cell differentiation; ganglioside metabolic process; and hard palate development. Part of Integrin alphav-beta8 complex. Is expressed in several structures, including axial skeleton; hindlimb phalanx; nervous system; reproductive system; and sensory organ. Orthologous to human ITGB8 (Integrin subunit beta 8). [provided by Alliance of Genome Resources, Apr 2022]

Itgb8 基因产物(1)

mRNA Protein Name
NM_177290.4 NP_796264.2 integrin beta-8 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Langerhans cell differentiation IGI
IGI: 通过遗传相互作用推断
19118215 MGI
acts upstream of or within ganglioside metabolic process IMP
IMP: 通过突变表型推断
16251442 MGI
acts upstream of or within hard palate development IGI
IGI: 通过遗传相互作用推断
19118215 MGI
acts upstream of or within immune response IGI
IGI: 通过遗传相互作用推断
19118215 MGI
acts upstream of or within response to virus IGI
IGI: 通过遗传相互作用推断
30952606 MGI
acts upstream of or within transforming growth factor beta receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
30952606 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of integrin alphav-beta8 complex IDA
IDA: 通过直接分析推断
22278742 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

integrin beta-8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itgb8 NCBI NCBI:3696
Macaca mulatta Itgb8 NCBI NCBI:707247