LGALS9 - galectin 9 Gene

中文名称：半乳糖凝集素 9

种属: Homo sapiens

同用名: HUAT; LGALS9A

关于 LGALS9

功能概要

半乳糖凝集素是β-半乳糖苷结合蛋白家族，参与调节细胞-细胞和细胞-基质相互作用。该基因编码的蛋白质是一种 S 型凝集素。它在霍奇金病组织中过度表达，可能参与 H&RS 细胞与其周围细胞之间的相互作用，因此可能在该疾病和/或其相关免疫缺陷的发病机制中发挥作用。已发现该基因的多个选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]