TARM1 - T cell-interacting, activating receptor on myeloid cells 1 Gene

中文名称：T 细胞相互作用，激活骨髓细胞 1 上的受体

种属: Homo sapiens

同用名: OLT-2

基因 ID: 441864 | 基因类型: protein coding

关于 TARM1

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,069,895-54,081,365 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 238 orthologues and 25 paralogues. Restricted expression toward bone marrow (RPKM 2.5).

功能概要

启用免疫球蛋白受体结合活性。参与 CD4 阳性、α-β T 细胞活化的负调节。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables immunoglobulin receptor binding activity. Involved in negative regulation of CD4-positive, alpha-beta T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TARM1 基因产物(2)

mRNA	Protein	Name
NM_001135686.3	NP_001129158.2	T-cell-interacting, activating receptor on myeloid cells protein 1 isoform 1 precursor
NM_001330650.1	NP_001317579.1	T-cell-interacting, activating receptor on myeloid cells protein 1 isoform 2

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables immunoglobulin receptor binding	IPI IPI: 通过物理相互作用推断	26311901	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in negative regulation of CD4-positive, alpha-beta T cell activation	IDA IDA: 通过直接分析推断	26311901	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in plasma membrane	IDA IDA: 通过直接分析推断	26311901	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TARM1 蛋白结构

Ig_2

0
100
200
279 a.a.

蛋白主名

其他名称

T-cell-interacting, activating receptor on myeloid cells protein 1

OSCAR-like transcript-2 protein

关联疾病

疾病名称

别名

Hypothyroidism, Central, With Testicular Enlargement

X-Linked Central Congenital Hypothyroidism With Late-Onset Testicular Enlargement	CHTE
Hypothyroidism, Central, And Testicular Enlargement	Igsf1 Deficiency Syndrome
X-Linked Central Congenital Hypothyroidism With Late-Onset Macroorchidism	Central Hypothyroidism And Testicular Enlargement
Hypothyroidism, Central, Testicular Enlargement

Facial Hemiatrophy

Parry-Romberg Syndrome

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14209	TARM1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS21061	Tarm1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS27578	Tarm1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	TARM1	VGNC	VGNC:35604
Rattus norvegicus	TARM1	RGD	RGD:1564272
Mus musculus	TARM1	MGD	MGI:2442280

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TARM1 - T cell-interacting, activating receptor on myeloid cells 1 Gene

关于 TARM1

功能概要

TARM1 基因产物(2)

TARM1 蛋白结构

关联疾病

直系同源

热门区域

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TARM1 - T cell-interacting, activating receptor on myeloid cells 1 Gene

关于 TARM1

功能概要

TARM1 基因产物(2)

TARM1 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z