1. Gene
  2. FOXB2 - forkhead box B2 Gene

FOXB2 - forkhead box B2 Gene

中文名称:叉头盒 B2

种属: Homo sapiens

同用名: FKH4; bA159H20.4

基因 ID: 442425 | 基因类型: protein coding

关于 FOXB2

Cytogenetic location: 9q21.2 Genomic coordinates (GRCh38): 9:77,019,655-77,020,953 (from NCBI)

This gene has 1 transcript (splice variant), 184 orthologues and 42 paralogues.

功能概要

预测可实现 DNA 结合转录因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。预计参与解剖结构形态发生;细胞分化; RNA 聚合酶 II 对转录的调控。预测位于核内。预测是染色质的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

FOXB2 基因产物(1)

mRNA Protein Name
NM_001013735.1 NP_001013757.1 forkhead box protein B2

FOXB2 蛋白结构

Forkhead

Forkhead: Forkhead domain (13 - 108)

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  • 432 a.a.
蛋白主名 其他名称

forkhead box protein B2

关联疾病

疾病名称 别名
Testicular Germ Cell Cancer

Germ Cell Tumor Of Testis

Testicular Germ Cell Tumor

Testicular Germ Cell Neoplasm

Testicular Malignant Germ Cell Tumor

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris FOXB2 VGNC VGNC:40947
Macaca mulatta FOXB2 VGNC VGNC:72555
Bos taurus FOXB2 VGNC VGNC:55046
Mus musculus FOXB2 MGD MGI:1347468
Felis catus FOXB2 VGNC VGNC:102928
Rattus norvegicus FOXB2 RGD RGD:1585019