2. Gene
  3. Xdh - xanthine dehydrogenase Gene

Xdh - xanthine dehydrogenase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：黄嘌呤脱氢酶

种属: Rattus norvegicus

同用名: XOR

基因 ID: 497811 | 基因类型: protein coding

关于 Xdh

Primary_assembly 6: 21,530,113-21,592,268 forward strand.mRatBN7.2:CM026979.1

This gene has 3 transcripts (splice variants), 208 orthologues, 3 paralogues and is associated with 76 phenotypes. Biased expression in Adrenal (RPKM 637.6), Spleen (RPKM 495.4) and 8 other tissues.

功能概要

该基因编码黄嘌呤脱氢酶蛋白家族的一个成员。编码的蛋白质已被确定为基于其执行机械不同功能的能力的兼职蛋白质。编码的蛋白质参与嘌呤降解，并作为脱氢酶和氧化酶发挥作用。 [RefSeq 提供，2014 年 1 月]

This gene encodes a member of the xanthine dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein is involved in purine degradation and functions as both a dehydrogenase and an oxidase. [provided by RefSeq, Jan 2014]

Xdh 基因产物(1)

mRNA Protein Name
NM_017154.2 NP_058850.2 xanthine dehydrogenase/oxidase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 2 iron, 2 sulfur cluster binding IDA
IDA: 通过直接分析推断
2549869 RGD
enables flavin adenine dinucleotide binding IDA
IDA: 通过直接分析推断
15878860 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
2549869 RGD
enables molybdopterin cofactor binding IDA
IDA: 通过直接分析推断
15878860 RGD
enables nitrite reductase (NO-forming) activity IDA
IDA: 通过直接分析推断
25537183 RGD
enables xanthine dehydrogenase activity IDA
IDA: 通过直接分析推断
2387845 RGD
enables xanthine oxidase activity IDA
IDA: 通过直接分析推断
2387845 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenosine catabolic process IDA
IDA: 通过直接分析推断
1619276 RGD
involved in allantoin metabolic process IDA
IDA: 通过直接分析推断
1619276 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
12653206 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
12653206 RGD
involved in guanine catabolic process IDA
IDA: 通过直接分析推断
3443108 RGD
involved in hypoxanthine catabolic process IDA
IDA: 通过直接分析推断
232638 RGD
involved in inosine catabolic process IDA
IDA: 通过直接分析推断
1619276 RGD
involved in response to aluminum ion IDA
IDA: 通过直接分析推断
11787993 RGD
involved in response to azide IEP
IEP: 通过表达模式推断
23174561 RGD
involved in response to carbon monoxide IEP
IEP: 通过表达模式推断
8248931 RGD
involved in response to hydrogen peroxide IEP
IEP: 通过表达模式推断
3162724 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
24378112 RGD
involved in xanthine catabolic process IDA
IDA: 通过直接分析推断
3443108 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
1619276 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
14728722 RGD
is active in peroxisome IDA
IDA: 通过直接分析推断
3443108 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Xdh 蛋白结构

PLN02906

PLN02906: cl33596 (22 - 1316)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1331 a.a.
蛋白主名 其他名称

xanthine dehydrogenase/oxidase

xanthine oxidase

xanthine oxidoreductase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15869 XDH Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS15870 Xdh Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS15871 Xdh Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Xdh NCBI NCBI:7498
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