2. Gene
  3. Rif1 - replication timing regulatory factor 1 Gene

Rif1 - replication timing regulatory factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D2Ertd145e; 5730435J01Rik; 6530403D07Rik

基因 ID: 51869 | 基因类型: protein coding

关于 Rif1

功能概要

Involved in positive regulation of histone H3-K9 methylation; regulation of nucleobase-containing compound metabolic process; and telomere organization. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and stem cell population maintenance. Located in chromosome and pronucleus. Is expressed in several structures, including early conceptus; hindgut epithelium; primordial germ cell; reproductive system; and urinary system. Orthologous to human RIF1 (replication timing regulatory factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Rif1 基因产物(3)

mRNA Protein Name
NM_001355414.1 NP_001342343.1 telomere-associated protein RIF1 isoform a
NM_001355415.1 NP_001342344.1 telomere-associated protein RIF1 isoform b
NM_175238.6 NP_780447.4 telomere-associated protein RIF1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17093407 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in negative regulation of double-strand break repair via homologous recombination IMP
IMP: 通过突变表型推断
23306437 MGI
involved in negative regulation of gene expression, epigenetic IDA
IDA: 通过直接分析推断
24735877 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
24735877 MGI
involved in positive regulation of double-strand break repair via nonhomologous end joining IMP
IMP: 通过突变表型推断
23306437 MGI
involved in positive regulation of isotype switching IMP
IMP: 通过突变表型推断
23306439 MGI
acts upstream of or within somatic stem cell population maintenance IMP
IMP: 通过突变表型推断
16518401 MGI
involved in subtelomeric heterochromatin formation IMP
IMP: 通过突变表型推断
24735877 MGI
involved in telomere maintenance IMP
IMP: 通过突变表型推断
24735877 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IMP
IMP: 通过突变表型推断
24735877 MGI
located in chromosome, telomeric region IDA
IDA: 通过直接分析推断
15042697 MGI
is active in chromosome, telomeric repeat region IDA
IDA: 通过直接分析推断
24735877 MGI
located in female pronucleus IDA
IDA: 通过直接分析推断
15042697 MGI
located in male pronucleus IDA
IDA: 通过直接分析推断
15042697 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15042697 MGI
located in site of double-strand break IDA
IDA: 通过直接分析推断
23306437 MGI
located in site of double-strand break IMP
IMP: 通过突变表型推断
23333305 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

telomere-associated protein RIF1

Rap1 interacting factor 1 homolog

mRif1

rap1-interacting factor 1 homolog

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06843 INSL6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07786 LRIF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS11971 RIF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19378 Rif1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20965 Insl6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25870 Rif1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rif1 NCBI NCBI:55183
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