1. Gene
  2. Chst3 - carbohydrate sulfotransferase 3 Gene

Chst3 - carbohydrate sulfotransferase 3 Gene

种属: Mus musculus

同用名: C6ST; GST-0; C6ST-1

基因 ID: 53374 | 基因类型: protein coding

关于 Chst3

功能概要

Enables chondroitin 6-sulfotransferase activity and proteoglycan sulfotransferase activity. Acts upstream of or within T cell homeostasis and chondroitin sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and respiratory system. Used to study schizophrenia. Human ortholog(s) of this gene implicated in osteochondrodysplasia and spondyloepiphyseal dysplasia with congenital joint dislocations. Orthologous to human CHST3 (carbohydrate sulfotransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Chst3 基因产物(2)

mRNA Protein Name
NM_001407025.1 NP_001393954.1 carbohydrate sulfotransferase 3
NM_016803.4 NP_058083.3 carbohydrate sulfotransferase 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chondroitin 6-sulfotransferase activity IDA
IDA: 通过直接分析推断
9597547 MGI
enables proteoglycan sulfotransferase activity IMP
IMP: 通过突变表型推断
11696535 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell homeostasis IMP
IMP: 通过突变表型推断
11696535 MGI
acts upstream of or within chondroitin sulfate biosynthetic process IDA
IDA: 通过直接分析推断
9597547 MGI
involved in chondroitin sulfate biosynthetic process IDA
IDA: 通过直接分析推断
9597547 MGI
acts upstream of or within chondroitin sulfate biosynthetic process IMP
IMP: 通过突变表型推断
11696535 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Golgi apparatus IDA
IDA: 通过直接分析推断
6781479 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

carbohydrate sulfotransferase 3

carbohydrate (chondroitin 6/keratan) sulfotransferase 3

chondroitin 6-O-sulfotransferase 1

chondroitin 6-sulfotransferase

galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0

重组 Chst3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76259 CHST3 Protein, Mouse (HEK293, His) O88199 (E39-T472) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chst3 NCBI NCBI:9469