2. Gene
  3. CASZ1 - castor zinc finger 1 Gene

CASZ1 - castor zinc finger 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蓖麻锌指 1

种属: Homo sapiens

同用名: CST; SRG; CAS11; ZNF693; dJ734G22.1

基因 ID: 54897 | 基因类型: protein coding

关于 CASZ1

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:10,636,604-10,796,646 (from NCBI)

This gene has 9 transcripts (splice variants), 210 orthologues and is associated with 1 phenotype. Broad expression in skin (RPKM 7.7), prostate (RPKM 5.8) and 22 other tissues.

功能概要

该基因编码的蛋白质是一种锌指转录因子。编码的蛋白质可能起到肿瘤抑制因子的作用，并且该基因中的单核苷酸多态性与血压变化有关。可变剪接导致编码不同蛋白质亚型的多个转录变体。[RefSeq 提供，2012 年 7 月]

The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

CASZ1 基因产物(2)

mRNA Protein Name
NM_001079843.3 NP_001073312.1 zinc finger protein castor homolog 1 isoform a
NM_017766.5 NP_060236.3 zinc finger protein castor homolog 1 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
27693370 GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
27693370 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
27693370 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
27693370 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
27693370 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger protein castor homolog 1

castor homolog 1, zinc finger

关联疾病

疾病名称 别名
Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy
Chromosome 1p36 Deletion Syndrome

1p36 Deletion Syndrome

Deletion 1p36

Monosomy 1p36

Subtelomeric 1p36 Deletion

Monosomy 1p36 Syndrome

Distal Monosomy 1p36

Del(1)(P36)

Deletion 1pter

Monosomy 1pter
Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01981 CASZ1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22415 Casz1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28938 Casz1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CASZ1 VGNC VGNC:106335
Bos taurus CASZ1 VGNC VGNC:50113
Felis catus CASZ1 VGNC VGNC:80156
Mus musculus CASZ1 MGD MGI:1196251
Canis familiaris CASZ1 VGNC VGNC:103664
Rattus norvegicus CASZ1 RGD RGD:1563533
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