2. Gene
  3. Smad9 - SMAD family member 9 Gene

Smad9 - SMAD family member 9 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MADH6; Madh8; Madh9; Smad8

基因 ID: 55994 | 基因类型: protein coding

关于 Smad9

功能概要

This gene encodes a member of a family of proteins that act as downstream effectors of the bone morphogenetic protein (BMP) signaling pathway. The encoded protein is phosphorylated by BMP receptors, which stimulates its binding to SMAD4 and translocation into the nucleus, where it functions as a regulator of transcription. Activity of this protein is important for embryonic development. Mutation of this gene results in defects in pulmonary vasculature. [provided by RefSeq, Mar 2013]

Smad9 基因产物(1)

mRNA Protein Name
NM_019483.5 NP_062356.3 mothers against decapentaplegic homolog 9
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11163184 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within BMP signaling pathway IDA
IDA: 通过直接分析推断
18590716 MGI
acts upstream of or within BMP signaling pathway IGI
IGI: 通过遗传相互作用推断
19224984 MGI
involved in BMP signaling pathway IGI
IGI: 通过遗传相互作用推断
19252488 MGI
involved in SMAD protein signal transduction IGI
IGI: 通过遗传相互作用推断
19252488 MGI
acts upstream of or within bone development IGI
IGI: 通过遗传相互作用推断
19224984 MGI
acts upstream of or within cartilage development IGI
IGI: 通过遗传相互作用推断
19224984 MGI
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: 通过直接分析推断
19103752 MGI
acts upstream of or within hindbrain development IMP
IMP: 通过突变表型推断
15899870 MGI
acts upstream of or within midbrain development IMP
IMP: 通过突变表型推断
15899870 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
18776146 MGI
involved in ureteric bud development IEP
IEP: 通过表达模式推断
14656760 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19103752 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18776146 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mothers against decapentaplegic homolog 9

MAD homolog 9

mothers against DPP homolog 9

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13399 SMAD9 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19036 Smad9 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25525 Smad9 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smad9 NCBI NCBI:4093
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