1. Gene
  2. Set - SET nuclear oncogene Gene

Set - SET nuclear oncogene Gene

种属: Mus musculus

同用名: TAF-I; I-2PP2A; StF-IT-1; 2610030F17Rik; 5730420M11Rik

基因 ID: 56086 | 基因类型: protein coding

关于 Set

功能概要

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within negative regulation of neuron apoptotic process. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; sensory organ; skin; and tooth. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human SET (SET nuclear proto-oncogene). [provided by Alliance of Genome Resources, Apr 2022]

Set 基因产物(2)

mRNA Protein Name
NM_001204875.2 NP_001191804.1 protein SET isoform 2
NM_023871.5 NP_076360.1 protein SET isoform 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
10716735 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein SET

SET translocation

phosphatase 2A inhibitor I2PP2A

template-activating factor I

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Set NCBI NCBI:6418
Macaca fascicularis Set NCBI NCBI:102118249
Rattus norvegicus Set NCBI NCBI:120101889
Macaca mulatta Set NCBI NCBI:693242