2. Gene
  3. Ncoa6 - nuclear receptor coactivator 6 Gene

Ncoa6 - nuclear receptor coactivator 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NRC; AIB3; ASC2; PRIP; ASC-2; Ncoa7; RAP250; mKIAA0181

基因 ID: 56406 | 基因类型: protein coding

关于 Ncoa6

功能概要

Enables chromatin binding activity and transcription coactivator activity. Acts upstream of or within animal organ development; histone H3-K4 trimethylation; and positive regulation of transcription, DNA-templated. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in breast cancer; colon cancer; and lung Cancer. Orthologous to human NCOA6 (nuclear receptor coactivator 6). [provided by Alliance of Genome Resources, Apr 2022]

Ncoa6 基因产物(4)

mRNA Protein Name
NM_001242558.2 NP_001229487.1 nuclear receptor coactivator 6 isoform 2
NM_001406325.1 NP_001393254.1 nuclear receptor coactivator 6 isoform 1
NM_001406326.1 NP_001393255.1 nuclear receptor coactivator 6 isoform 1
NM_019825.4 NP_062799.2 nuclear receptor coactivator 6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
12446761 MGI
enables chromatin-protein adaptor activity IMP
IMP: 通过突变表型推断
17021013 MGI
enables histone methyltransferase binding IPI
IPI: 通过物理相互作用推断
17021013 MGI
enables transcription coactivator activity IDA
IDA: 通过直接分析推断
10788465 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
12556486 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
12368298 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: 通过突变表型推断
12368298 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
10681503 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
17021013 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
10788465 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
10681503 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor coactivator 6

PPAR interacting protein PRIP

PPAR-interacting protein

activating signal cointegrator 2

amplified in breast cancer protein 3

cancer-amplified transcriptional coactivator ASC-2

nuclear receptor coactivator RAP250

nuclear receptor-activating protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09094 NCOA6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20060 Ncoa6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26564 Ncoa6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncoa6 NCBI NCBI:23054
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