2. Gene
  3. Kcnd3 - potassium voltage-gated channel, Shal-related family, member 3 Gene

Kcnd3 - potassium voltage-gated channel, Shal-related family, member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Kncd3; Kv4.3

基因 ID: 56543 | 基因类型: protein coding

关于 Kcnd3

功能概要

Enables voltage-gated Potassium Channel activity involved in cardiac muscle cell action potential repolarization. Acts upstream of or within cardiac conduction; cardiac muscle cell action potential involved in contraction; and potassium ion export across plasma membrane. Located in membrane. Is integral component of postsynaptic specialization membrane. Is active in GABA-ergic synapse. Is expressed in heart and heart ventricle. Human ortholog(s) of this gene implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22. Orthologous to human KCND3 (potassium voltage-gated channel subfamily D member 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcnd3 基因产物(2)

mRNA Protein Name
NM_001039347.2 NP_001034436.1 potassium voltage-gated channel subfamily D member 3 isoform 1 precursor
NM_019931.2 NP_064315.1 potassium voltage-gated channel subfamily D member 3 isoform 2 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15662035 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
17122053 MGI
located in membrane IDA
IDA: 通过直接分析推断
18603586 MGI
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
17122053 MGI
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
8831489 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily D member 3

potassium channel Kv4.3L

potassium channel Kv4.3M

voltage-gated potassium channel subunit Kv4.3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07114 KCND3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20972 Kcnd3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27489 Kcnd3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnd3 NCBI NCBI:3752
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