2. Gene
  3. ELAPOR1 - endosome-lysosome associated apoptosis and autophagy regulator 1 Gene

ELAPOR1 - endosome-lysosome associated apoptosis and autophagy regulator 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：内体-溶酶体相关细胞凋亡和自噬调节因子 1

种属: Homo sapiens

同用名: EIG121; KIAA1324

基因 ID: 57535 | 基因类型: protein coding

关于 ELAPOR1

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:109,114,115-109,206,781 (from NCBI)

This gene has 14 transcripts (splice variants), 206 orthologues and 1 paralogue. Biased expression in stomach (RPKM 32.4), salivary gland (RPKM 26.9) and 13 other tissues.

功能概要

该基因的表达由雌激素诱导，编码的蛋白质已被表征为跨膜蛋白。已发现编码的蛋白质与某些癌的存活率相关 (PMID：21102415) ，并且可能对细胞对压力的反应很重要 (PMID：21072319) 。可变剪接导致多个转录本变体。[RefSeq 提供，2012 年 5 月]

Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

ELAPOR1 基因产物(4)

mRNA Protein Name
NM_001267048.2 NP_001253977.2 endosome/lysosome-associated apoptosis and autophagy regulator 1 isoform 2
NM_001284352.2 NP_001271281.1 endosome/lysosome-associated apoptosis and autophagy regulator 1 isoform 4
NM_001284353.2 NP_001271282.1 endosome/lysosome-associated apoptosis and autophagy regulator 1 isoform 5
NM_020775.5 NP_065826.3 endosome/lysosome-associated apoptosis and autophagy regulator 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autophagosome assembly IMP
IMP: 通过突变表型推断
21072319 GOA
involved in cellular response to starvation IMP
IMP: 通过突变表型推断
21072319 GOA
involved in positive regulation of autophagosome assembly IMP
IMP: 通过突变表型推断
21072319 GOA
involved in positive regulation of vacuole organization IMP
IMP: 通过突变表型推断
21072319 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
colocalizes with late endosome IDA
IDA: 通过直接分析推断
21072319 GOA
colocalizes with lysosome IDA
IDA: 通过直接分析推断
21072319 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
21072319 GOA
colocalizes with trans-Golgi network IDA
IDA: 通过直接分析推断
21072319 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

endosome/lysosome-associated apoptosis and autophagy regulator 1

estrogen-induced gene 121 protein

重组 ELAPOR1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78759 ELAPOR1 Protein, Human (sf9, His) Q6UXG2 (T42-K910) ≥95%

关联疾病

疾病名称 别名
Baastrup'S Syndrome

Kissing Spine

Baastrup Syndrome

Kissing Spine, Site Unspecified

Osteoarthrosis Interspinalis

Overriding Of Dorsal Spinous Processes

Localised Idiopathic Skeletal Hyperostosis

Baastrup Disease
Estrogen Excess

Hyperestrogenism
Female Reproductive Endometrioid Cancer

Endometrioid Tumor

Endometrioid Neoplasm

Female Reproductive Endometrioid Neoplasm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04293 ELAPOR1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ELAPOR1 VGNC VGNC:30567
Rattus norvegicus ELAPOR1 RGD RGD:1310209
Canis familiaris ELAPOR1 VGNC VGNC:42364
Mus musculus ELAPOR1 MGD MGI:1923930
Felis catus ELAPOR1 VGNC VGNC:63095
Others ELAPOR1 NCBI
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