2. Gene
  3. Bcl11b - B cell leukemia/lymphoma 11B Gene

Bcl11b - B cell leukemia/lymphoma 11B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rit1; Ctip2; BCL-11B; 9130430L19Rik; B630002E05Rik

基因 ID: 58208 | 基因类型: protein coding

关于 Bcl11b

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; cell morphogenesis involved in differentiation; and regulation of keratinocyte proliferation. Located in neuron projection and nucleus. Is expressed in several structures, including alimentary system; central nervous system; craniocervical region bone; nose; and skin. Human ortholog(s) of this gene implicated in immunodeficiency 49. Orthologous to human BCL11B (BAF chromatin remodeling complex subunit BCL11B). [provided by Alliance of Genome Resources, Apr 2022]

Bcl11b 基因产物(3)

mRNA Protein Name
NM_001079883.1 NP_001073352.1 B-cell lymphoma/leukemia 11B isoform a
NM_001286343.1 NP_001273272.1 B-cell lymphoma/leukemia 11B isoform c
NM_021399.2 NP_067374.2 B-cell lymphoma/leukemia 11B isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
18595722 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16809611 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16809611 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16809611 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of T cell apoptotic process IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of or within T cell differentiation in thymus IMP
IMP: 通过突变表型推断
16670294 MGI
acts upstream of or within T cell receptor V(D)J recombination IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of or within alpha-beta T cell differentiation IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of or within axonogenesis IMP
IMP: 通过突变表型推断
15664173 MGI
acts upstream of or within central nervous system neuron differentiation IGI
IGI: 通过遗传相互作用推断
18215621 MGI
acts upstream of or within commitment of neuronal cell to specific neuron type in forebrain IGI
IGI: 通过遗传相互作用推断
23144223 MGI
acts upstream of or within epithelial cell morphogenesis IMP
IMP: 通过突变表型推断
19251658 MGI
acts upstream of or within keratinocyte development IMP
IMP: 通过突变表型推断
19092943 MGI
acts upstream of or within negative regulation of T cell apoptotic process IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
12565905 MGI
acts upstream of or within negative regulation of thymocyte apoptotic process IMP
IMP: 通过突变表型推断
16670294 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: 通过突变表型推断
19251658 MGI
acts upstream of or within olfactory bulb axon guidance IMP
IMP: 通过突变表型推断
21752992 MGI
acts upstream of or within positive T cell selection IMP
IMP: 通过突变表型推断
17998389 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16809611 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16809611 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of or within post-embryonic camera-type eye development IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
21752992 MGI
acts upstream of or within regulation of keratinocyte proliferation IMP
IMP: 通过突变表型推断
19092943 MGI
acts upstream of or within regulation of lipid metabolic process IMP
IMP: 通过突变表型推断
19092943 MGI
acts upstream of or within regulation of neuron differentiation IMP
IMP: 通过突变表型推断
21752992 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
19092943 MGI
acts upstream of or within striatal medium spiny neuron differentiation IMP
IMP: 通过突变表型推断
18199763 MGI
acts upstream of thymocyte apoptotic process IMP
IMP: 通过突变表型推断
16670294 MGI
acts upstream of or within thymus development IMP
IMP: 通过突变表型推断
12717433 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16809611 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16809611 MGI
acts upstream of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
12717433 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SWI/SNF complex IDA
IDA: 通过直接分析推断
23644491 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
18255031 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
25100583 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12565905 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

B-cell lymphoma/leukemia 11B

B-cell CLL/lymphoma 11B

B-cell lymphoma/leukaemia 11B

COUP-TF-interacting protein 2

mRit1

radiation-induced tumor suppressor gene 1 protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01414 BCL11B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21827 Bcl11b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28344 Bcl11b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcl11b NCBI NCBI:64919
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