2. Gene
  3. Apln - apelin Gene

Apln - apelin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Apel

基因 ID: 58812 | 基因类型: protein coding

关于 Apln

功能概要

Enables apelin receptor binding activity and identical protein binding activity. Involved in several processes, including apelin receptor signaling pathway; positive regulation of peptide hormone secretion; and regulation of blood circulation. Located in extracellular space and perinuclear region of cytoplasm. Used to study congestive heart failure. Biomarker of colitis; congestive heart failure; hypertension; and obesity. Orthologous to human APLN (apelin). [provided by Alliance of Genome Resources, Apr 2022]

Apln 基因产物(1)

mRNA Protein Name
NM_031612.3 NP_113800.1 apelin preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables apelin receptor binding IDA
IDA: 通过直接分析推断
11336787 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15486224 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in apelin receptor signaling pathway IDA
IDA: 通过直接分析推断
11359874 RGD
involved in drinking behavior IMP
IMP: 通过突变表型推断
10617103 RGD
involved in feeding behavior IMP
IMP: 通过突变表型推断
14642423 RGD
involved in negative regulation of blood pressure IDA
IDA: 通过直接分析推断
15486224 RGD
involved in negative regulation of blood pressure IMP
IMP: 通过突变表型推断
10617103 RGD
involved in negative regulation of systemic arterial blood pressure IDA
IDA: 通过直接分析推断
12798955 RGD
involved in negative regulation of vasoconstriction IMP
IMP: 通过突变表型推断
17318790 RGD
involved in positive regulation of G protein-coupled receptor internalization IDA
IDA: 通过直接分析推断
11359874 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
14670994 RGD
involved in positive regulation of corticotropin secretion IMP
IMP: 通过突变表型推断
16896162 RGD
involved in positive regulation of corticotropin-releasing hormone secretion IMP
IMP: 通过突变表型推断
15541902 RGD
involved in positive regulation of heart contraction IMP
IMP: 通过突变表型推断
26611206 RGD
involved in positive regulation of heart rate IDA
IDA: 通过直接分析推断
12798955 RGD
involved in positive regulation of heat generation IMP
IMP: 通过突变表型推断
15541902 RGD
involved in positive regulation of phosphorylation IMP
IMP: 通过突变表型推断
16556853 RGD
involved in regulation of body fluid levels IMP
IMP: 通过突变表型推断
12787050 RGD
involved in regulation of the force of heart contraction IMP
IMP: 通过突变表型推断
17055480 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
16674982 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15166125 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

apelin

APJ endogenous ligand

apelin, AGTRL1 ligand

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00822 APLN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18461 Apln Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24942 Apln Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Apln NCBI NCBI:8862
Mus musculus Apln NCBI NCBI:30878
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