1. Gene
  2. S100A10 - S100 calcium binding protein A10 Gene

S100A10 - S100 calcium binding protein A10 Gene

中文名称:S100 钙结合蛋白 A10

种属: Homo sapiens

同用名: 42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG

基因 ID: 6281 | 基因类型: protein coding

关于 S100A10

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:151,982,915-151,993,859 (from NCBI)

This gene has 4 transcripts (splice variants), 246 orthologues and 21 paralogues. Broad expression in colon (RPKM 299.3), esophagus (RPKM 210.9) and 22 other tissues.

功能概要

由该基因编码的蛋白质是包含 2 个 EF 手钙结合基序的 S100 蛋白质家族的成员。 S100 蛋白定位于多种细胞的细胞质和/或细胞核,并参与许多细胞过程的调节,例如细胞周期进程和分化。 S100 基因包括至少 13 个成员,它们成簇地位于染色体 1q21 上。这种蛋白质可能在胞吐作用和胞吞作用中起作用。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]

S100A10 基因产物(1)

mRNA Protein Name
NM_002966.3 NP_002957.1 protein S100-A10

S100A10 蛋白结构

S_100

S_100: S-100/ICaBP type calcium binding domain (5 - 45)

  • 0
  • 97 a.a.
蛋白主名 其他名称

protein S100-A10

S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11))

重组 S100A10 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74586 S100A10 Protein, Human (His) P60903 (P2-K97) ≥95%

关联疾病

疾病名称 别名
Trachea Leiomyoma

Tracheal Neoplasms

Leiomyoma Of The Trachea

Tracheal Neoplasm

Tracheal Leiomyoma

Conjunctival Intraepithelial Neoplasm

Intraepithelial Neoplasia Of Conjunctiva

Conjunctival Intraepithelial Neoplasia

Barrett'S Adenocarcinoma

Barrett Adenocarcinoma

Adenocarcinoma Arising In Barrett'S Mucosa

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus S100A10 MGD MGI:1339468
Rattus norvegicus S100A10 RGD RGD:628655
Bos taurus S100A10 VGNC VGNC:34237
Felis catus S100A10 VGNC VGNC:80348
Macaca mulatta S100A10 VGNC VGNC:106491
Others S100A10 NCBI