2. Gene
  3. Rad50 - RAD50 double strand break repair protein Gene

Rad50 - RAD50 double strand break repair protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 64012 | 基因类型: protein coding

关于 Rad50

功能概要

Enables double-stranded DNA binding activity. Involved in several processes, including cellular response to DNA damage stimulus; negative regulation of viral entry into host cell; and response to human chorionic gonadotropin. Located in several cellular components, including inclusion body; nuclear lumen; and perinuclear region of cytoplasm. Used to study liver cirrhosis and myocardial infarction. Human ortholog(s) of this gene implicated in transitional cell carcinoma. Orthologous to human RAD50 (RAD50 double strand break repair protein). [provided by Alliance of Genome Resources, Apr 2022]

Rad50 基因产物(1)

mRNA Protein Name
NM_022246.2 NP_071582.2 DNA repair protein RAD50
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
21956462 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12615909 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
18212738 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IEP
IEP: 通过表达模式推断
11056294 RGD
involved in heart development IEP
IEP: 通过表达模式推断
10908350 RGD
involved in negative regulation of viral entry into host cell IMP
IMP: 通过突变表型推断
22850678 RGD
involved in response to human chorionic gonadotropin IEP
IEP: 通过表达模式推断
23239112 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
10855503 RGD
located in condensed nuclear chromosome IDA
IDA: 通过直接分析推断
10855503 RGD
located in inclusion body IDA
IDA: 通过直接分析推断
18212738 RGD
located in nucleoplasm IDA
IDA: 通过直接分析推断
18212738 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
18212738 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA repair protein RAD50

RAD50 homolog, double strand break repair protein

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-117693 (E/Z)-Mirin Inhibitor 99.22% 否
HY-19959 Mirin 99.63% 否
HY-149972 Antitumor agent-96 Inducer / 否
HY-RS11602 RAD50 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18404 Rad50 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24885 Rad50 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rad50 NCBI NCBI:10111
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