2. Gene
  3. ENTPD1 - Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 Gene

ENTPD1 - Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: NTPDase-1

基因 ID: 64519 | 基因类型: protein coding

关于 ENTPD1

功能概要

Enables ATP hydrolysis activity; adenosine-diphosphatase activity; and identical protein binding activity. Involved in several processes, including cellular response to cytokine stimulus; response to amino acid; and response to purine-containing compound. Located in several cellular components, including basolateral plasma membrane; postsynaptic density; and synaptic vesicle. Biomarker of demyelinating disease; hypothyroidism; intrahepatic cholestasis; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 64. Orthologous to human ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

ENTPD1 基因产物(1)

mRNA Protein Name
NM_022587.2 NP_072109.2 ectonucleoside triphosphate diphosphohydrolase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ADP phosphatase activity IDA
IDA: 通过直接分析推断
18841405 RGD
enables ATP hydrolysis activity IDA
IDA: 通过直接分析推断
18841405 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12694193 RGD
enables nucleoside diphosphate phosphatase activity IDA
IDA: 通过直接分析推断
9221928 RGD
enables ribonucleoside triphosphate phosphatase activity IDA
IDA: 通过直接分析推断
9221928 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to aluminum ion IEP
IEP: 通过表达模式推断
20832780 RGD
involved in cellular response to interferon-alpha IEP
IEP: 通过表达模式推断
23990338 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
23990338 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
23990338 RGD
involved in negative regulation of ATP biosynthetic process IMP
IMP: 通过突变表型推断
21325440 RGD
involved in negative regulation of dopamine secretion IMP
IMP: 通过突变表型推断
21325440 RGD
involved in response to ATP IEP
IEP: 通过表达模式推断
20223894 RGD
involved in response to L-arginine IEP
IEP: 通过表达模式推断
12615083 RGD
involved in response to auditory stimulus IEP
IEP: 通过表达模式推断
15183524 RGD
involved in response to caffeine IEP
IEP: 通过表达模式推断
12834266 RGD
involved in response to gamma radiation IEP
IEP: 通过表达模式推断
19169047 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
11383876 RGD
involved in response to proline IEP
IEP: 通过表达模式推断
17407768 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
11383876 RGD
located in cell surface IDA
IDA: 通过直接分析推断
15673609 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
18997343 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15183524 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
15730886 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
9593967 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ectonucleoside triphosphate diphosphohydrolase 1

ATPDase

NTPDase 1

ecto-ATP diphosphohydrolase 1

ecto-ATPDase 1

ecto-ATPase 1

ecto-apyrase

lymphoid cell activation antigen

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990068 Perenostobart 97.00% Phase 2
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04395 ENTPD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18563 Entpd1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25045 Entpd1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991444 IPH5201 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens ENTPD1 NCBI NCBI:953
Mus musculus ENTPD1 NCBI NCBI:12495
Macaca mulatta ENTPD1 NCBI
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