2. Gene
  3. FNDC3B - fibronectin type III domain containing 3B Gene

FNDC3B - fibronectin type III domain containing 3B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 III 型纤连蛋白结构域 3B

种属: Homo sapiens

同用名: FAD104; PRO4979; YVTM2421

基因 ID: 64778 | 基因类型: protein coding

关于 FNDC3B

Cytogenetic location: 3q26.31 Genomic coordinates (GRCh38): 3:172,039,578-172,401,669 (from NCBI)

This gene has 12 transcripts (splice variants), 226 orthologues and 11 paralogues. Ubiquitous expression in placenta (RPKM 15.6), thyroid (RPKM 11.7) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计在几个过程的上游或内部起作用，包括成骨细胞分化的负调节；底物粘附依赖性细胞扩散；和 II 型肺细胞分化。预测位于内质网。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to act upstream of or within several processes, including negative regulation of osteoblast differentiation; substrate adhesion-dependent cell spreading; and type II pneumocyte differentiation. Predicted to be located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

FNDC3B 基因产物(2)

mRNA Protein Name
NM_001135095.2 NP_001128567.1 fibronectin type III domain-containing protein 3B
NM_022763.4 NP_073600.3 fibronectin type III domain-containing protein 3B
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FNDC3B 蛋白结构

fn3

fn3: Fibronectin type III domain (279 - 361)

fn3

fn3: Fibronectin type III domain (384 - 463)

fn3

fn3: Fibronectin type III domain (478 - 559)

fn3

fn3: Fibronectin type III domain (574 - 656)

fn3

fn3: Fibronectin type III domain (684 - 755)

fn3

fn3: Fibronectin type III domain (783 - 849)

fn3

fn3: Fibronectin type III domain (886 - 947)

fn3

fn3: Fibronectin type III domain (961 - 1042)

fn3

fn3: Fibronectin type III domain (1058 - 1129)

  • 0
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  • 400
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  • 800
  • 1000
  • 1204 a.a.
蛋白主名 其他名称

fibronectin type III domain-containing protein 3B

HCV NS5A-binding protein 37

关联疾病

疾病名称 别名
Urethra Clear Cell Adenocarcinoma

Clear Cell Adenocarcinoma Of The Urethra

Urethral Clear Cell Adenocarcinoma
Urethra Adenocarcinoma

Adenocarcinoma Of The Urethra

Urethral Adenocarcinoma
Keratoconus

Kc

Conical Cornea

Noninflammatory Corneal Thining

Bulging Cornea

Cornea Conical

Acquired Conus Of Cornea
Irregular Astigmatism
Urethra Cancer

Cancer Of Urethra

Malignant Tumour Of Urethra

Malignant Urethral Neoplasm

Urethral Ca
Corneal Ectasia
Gastric Tubular Adenocarcinoma

Tubular Adenocarcinoma Of Stomach
Glaucoma, Primary Open Angle

Glaucoma 1, Open Angle, E

Primary Open Angle Glaucoma

POAG

Adult-Onset Primary Open Angle Glaucoma

Chronic Simple Glaucoma

GLC1E

Primary Open Angle Glaucoma 1e

Glaucoma, Open Angle, Primary
Fuchs' Endothelial Dystrophy

Fuchs Endothelial Corneal Dystrophy

Fuchs Endothelial Dystrophy

Fuchs Dystrophy

Fced

Fuchs' Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy

Fuchs Atrophy

Fuchs Corneal Dystrophy

Endoepithelial Corneal Dystrophy

Fecd

Late Hereditary Endothelial Dystrophy

Corneal Dystrophy, Fuchs Endothelial

Dystrophy, Corneal, Fuchs Endothelial

Corneal Dystrophy, Fuchs' Endothelial, 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05020 FNDC3B Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus FNDC3B VGNC VGNC:29063
Felis catus FNDC3B VGNC VGNC:62320
Rattus norvegicus FNDC3B RGD RGD:1311673
Mus musculus FNDC3B MGD MGI:1919257
Canis familiaris FNDC3B VGNC VGNC:40929
Macaca mulatta FNDC3B VGNC VGNC:72564
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